HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: BRAP (Q7Z569)
BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63)
Gene: BRAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.595

Property	Details
Experiments	25820252, 23707952
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 592
+	Hs
		725080 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		UBP20_HUMAN (296-560): 3.22e-62: 223: 15.75
+	Hs
		725271 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		UBP20_HUMAN (296-560): 3.22e-62: 223: 15.75
+	Hs
		1068706 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		UBP20_HUMAN (296-560): 3.22e-62: 223: 15.75
+	Hs
		724889 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		UBP45_HUMAN (272-583): 8.15e-59: 212: 13.51
+	Hs
		725186 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		UBP45_HUMAN (272-583): 8.15e-59: 212: 13.51
+	Hs
		1377850 MYH4_HUMAN (1-831): 9.18e-34: 145: 12.50		UBP15_HUMAN (423-569): 1.13e-36: 148: 9.93
+	Hs
		1356646 MYH2_HUMAN (1-869): 2.82e-33: 143: 12.06		UBP15_HUMAN (423-569): 1.13e-36: 148: 9.93
+	Hs
		725273 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		UBP15_HUMAN (423-569): 1.13e-36: 148: 9.93
+	Hs
		725053 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		HDAC6_HUMAN (301-392): 2.71e-31: 131: 24.49
+	Hs
		725261 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		HDAC6_HUMAN (301-392): 2.71e-31: 131: 24.49
+	Hs
		1068690 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		HDAC6_HUMAN (301-392): 2.71e-31: 131: 24.49
+	Mm
		1143175 MYH10_MOUSE (5-834): 3.93e-31: 136: 11.65		HDAC6_MOUSE (301-392): 6.21e-30: 127: 24.49
+	Hs
		728525 MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41		HDAC6_HUMAN (301-392): 2.71e-31: 131: 24.49
+	Hs
		1059289 GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49		HDAC6_HUMAN (301-392): 2.71e-31: 131: 24.49