HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: PK1IP (Q9NWT1)
p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)
Gene: PAK1IP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 392
+	Hs
		1099279 SRSF5_HUMAN (14-183): 8.07e-61: 194: 41.48		PK1IP_HUMAN (1-392): 2.24e-91: 282: 100.00
+	Hs
		1099573 SRSF6_HUMAN (17-200): 2.59e-57: 187: 40.51		PK1IP_HUMAN (1-392): 2.24e-91: 282: 100.00
+	Hs
		1062134 SRSF4_HUMAN (17-243): 1.37e-49: 171: 37.66		PK1IP_HUMAN (1-392): 2.24e-91: 282: 100.00
+	Hs
		1099004 SRSF9_HUMAN (1-239): 4.19e-66: 206: 60.25		FBXW7_HUMAN (109-377): 1.31e-48: 176: 13.09
+	Hs
		964885 SRSF1_HUMAN (1-235): 5.46e-49: 163: 100.00		WDR5_HUMAN (74-367): 4.84e-67: 217: 17.39
+	Hs
		1061213 SRSF1_HUMAN (1-235): 5.46e-49: 163: 100.00		FBW1A_HUMAN (2-286): 8.37e-64: 216: 16.72
+	Hs
		1099190 SRSF5_HUMAN (14-183): 8.07e-61: 194: 41.48		FBXW7_HUMAN (109-377): 1.31e-48: 176: 13.09
+	Hs
		550204 PABP1_HUMAN (7-203): 1.69e-37: 140: 17.07		WDR5_HUMAN (74-367): 4.84e-67: 217: 17.39
+	Hs
		550532 PABP1_HUMAN (7-203): 1.69e-37: 140: 17.07		FBW1A_HUMAN (2-286): 8.37e-64: 216: 16.72
+	Hs
		1062067 SRSF4_HUMAN (17-243): 1.37e-49: 171: 37.66		FBXW7_HUMAN (109-377): 1.31e-48: 176: 13.09
+	Hs
		1061080 SRSF1_HUMAN (1-235): 5.46e-49: 163: 100.00		FBXW7_HUMAN (109-377): 1.31e-48: 176: 13.09
+	Hs
		1099276 SRSF5_HUMAN (14-183): 8.07e-61: 194: 41.48		NLE1_HUMAN (154-389): 2.37e-36: 139: 10.04
+	Hs
		1016675 SRSF3_HUMAN (15-99): 9.37e-28: 105: 43.53		FBW1A_HUMAN (2-286): 8.37e-64: 216: 16.72
+	Hs
		964979 SRSF7_HUMAN (14-105): 7.37e-23: 94.8: 40.22		WDR5_HUMAN (74-367): 4.84e-67: 217: 17.39
+	Hs
		550511 PABP1_HUMAN (7-203): 1.69e-37: 140: 17.07		FBW1B_HUMAN (3-231): 1.4e-43: 160: 16.87
+	Hs
		1099468 SRSF6_HUMAN (17-200): 2.59e-57: 187: 40.51		SNR40_HUMAN (197-383): 6.44e-23: 100: 12.33
+	Hs
		1160027 SRSF7_HUMAN (14-105): 7.37e-23: 94.8: 40.22		FBXW7_HUMAN (109-377): 1.31e-48: 176: 13.09
+	Hs
		1016642 SRSF3_HUMAN (15-99): 9.37e-28: 105: 43.53		NLE1_HUMAN (154-389): 2.37e-36: 139: 10.04
+	Hs
		1016554 SRSF3_HUMAN (15-99): 9.37e-28: 105: 43.53		SNR40_HUMAN (197-383): 6.44e-23: 100: 12.33
+	Hs
		984072 SRSF3_HUMAN (15-99): 9.37e-28: 105: 43.53		GBB2_HUMAN (179-376): 3.51e-12: 68.7: 10.00