HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 27173435, 12393879, 24981860, 35271311, 36765085, 31839598, 16902406, 16682447, 28514442, 30021884, 33961781, 37071682, 35575683, 39422127, 19214185, 16713563, 21055985, unassigned3799
Identification Methods affinity chromatography technology, pull down, cross-linking study, biochemical, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH1_SSRP1-like~Rttp106-like_middle, PH1_SSRP1-like~SPT16, POB3_N~SPT16, Rttp106-like_middle~Rttp106-like_middle, Rttp106-like_middle~SPT16, SPT16~SSrecog
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0006281 - DNA repair
and 4 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 709
Hs

1 1047
+ Dm
+ Ce
+ Ce
+ At
+ Tt
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025