HitPredict

Interactor 1: P2RY6 (Q15077)
P2Y purinoceptor 6 (P2Y6)
Gene: P2RY6

Interactor 2: Q5SZE2 (Q5SZE2)
Ceramide synthase 2
Gene: CERS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	30833792
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 128
+	Hs
		814586 P2RY1_HUMAN (3-328): 1.51e-86: 266: 34.34		CERS2_HUMAN (1-128): 4.3e-63: 198: 100.00
+	Hs
		814578 P2RY1_HUMAN (3-328): 1.51e-86: 266: 34.34		CERS6_HUMAN (8-128): 2.95e-59: 188: 45.46
+	Hs
		1067580 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		CERS2_HUMAN (1-128): 4.3e-63: 198: 100.00
+	Hs
		1031047 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		CERS2_HUMAN (1-128): 4.3e-63: 198: 100.00
+	Hs
		849683 CCR6_HUMAN (16-325): 2.16e-67: 217: 22.36		CERS5_HUMAN (2-127): 7.07e-62: 195: 39.37
+	Hs
		895677 CXCR4_HUMAN (4-321): 1.82e-67: 216: 25.94		CERS5_HUMAN (2-127): 7.07e-62: 195: 39.37
+	Hs
		1030979 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		CERS6_HUMAN (8-128): 2.95e-59: 188: 45.46
+	Hs
		666327 NK3R_HUMAN (13-319): 6.34e-64: 210: 22.12		CERS5_HUMAN (2-127): 7.07e-62: 195: 39.37
+	Hs
		849677 CCR6_HUMAN (16-325): 2.16e-67: 217: 22.36		CERS6_HUMAN (8-128): 2.95e-59: 188: 45.46
+	Hs
		781097 OPRX_HUMAN (18-326): 2.97e-63: 206: 23.55		CERS2_HUMAN (1-128): 4.3e-63: 198: 100.00
+	Hs
		723335 APJ_HUMAN (28-323): 1.65e-65: 212: 25.99		CERS6_HUMAN (8-128): 2.95e-59: 188: 45.46
+	Hs
		674858 AGTR1_HUMAN (14-325): 2.28e-63: 206: 26.43		CERS6_HUMAN (8-128): 2.95e-59: 188: 45.46
+	Hs
		781078 OPRX_HUMAN (18-326): 2.97e-63: 206: 23.55		CERS6_HUMAN (8-128): 2.95e-59: 188: 45.46
+	Hs
		172114 GP182_HUMAN (22-311): 1.07e-25: 107: 26.87		CERS5_HUMAN (2-127): 7.07e-62: 195: 39.37