HitPredict

Interactor 1: P2RY6 (Q15077)
P2Y purinoceptor 6 (P2Y6)
Gene: P2RY6

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 328 Hs			1 923
+	Hs
		1031125 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		782494 P2RY2_HUMAN (18-307): 1.28e-67: 218: 42.07		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		163184 LPAR4_HUMAN (17-313): 7.7e-86: 264: 29.87		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		162764 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		162701 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		162445 APJ_HUMAN (28-323): 1.65e-65: 212: 25.99		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		297174 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		IPO13_HUMAN (5-923): 2.1e-143: 452: 21.02
+	Hs
		297173 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		IPO13_HUMAN (5-923): 2.1e-143: 452: 21.02
+	Hs
		312275 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		IPO7_HUMAN (13-813): 8.63e-101: 340: 11.63
+	Hs
		207938 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		XPOT_HUMAN (12-770): 1.76e-93: 318: 15.10
+	Hs
		1067562 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		TNPO1_HUMAN (66-784): 4e-93: 316: 12.71
+	Hs
		207933 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		XPOT_HUMAN (12-770): 1.76e-93: 318: 15.10
+	Hs
		155568 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		TNPO2_HUMAN (68-784): 3.33e-92: 313: 12.26
+	Hs
		178168 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		127275 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		IPO5_HUMAN (68-703): 1.92e-86: 301: 13.24
+	Hs
		178157 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		178124 P2RY2_HUMAN (18-307): 1.28e-67: 218: 42.07		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		178120 APJ_HUMAN (28-323): 1.65e-65: 212: 25.99		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		1067620 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		XPO5_HUMAN (9-614): 3.04e-22: 105: 14.21
+	Hs
		1031082 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		XPO5_HUMAN (9-614): 3.04e-22: 105: 14.21