HitPredict

Interactor 1: TEBP (Q15185)
Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)
Gene: PTGES3

Interactor 2: AGO4 (Q9HCK5)
Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4)
Gene: AGO4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 19167051
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 861
+	Hs
		1069561 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		AGO1_HUMAN (8-861): 0: 1157: 83.49
+	Hs
		1069560 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		AGO2_HUMAN (12-861): 0: 1151: 78.94
+	Mm
		1208655 TEBP_MOUSE (1-160): 2.5e-54: 170: 98.75		AGO2_MOUSE (5-861): 0: 1153: 78.19
+	Hs
		1069514 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		AGO3_HUMAN (5-861): 0: 1146: 81.18
+	Hs
		59979 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		A4FVC0_HUMAN (62-861): 0: 1080: 79.88
+	Zm
		26941 A0A1D6PTR0_MAIZE (2-141): 6.79e-40: 135: 23.40		A0A1D6JCD6_MAIZE (2-860): 0: 1038: 38.41
+	Hs
		1069473 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		PIWL1_HUMAN (17-828): 0: 739: 22.24
+	Hs
		1069441 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		PIWL2_HUMAN (6-824): 0: 699: 22.24
+	Hs
		1069396 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		PIWL4_HUMAN (21-824): 0: 672: 21.68
+	Hs
		1069371 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		Q5TA56_HUMAN (5-208): 5.12e-93: 293: 67.14