HitPredict

Interactor 1: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Interactor 2: REN3B (Q9BZI7)
Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X)
Gene: UPF3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	11546874, 16601204, 16209946
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 1 others more... GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 483
+	Hs
		1318150 RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38		REN3B_HUMAN (1-483): 2.94e-73: 241: 100.00
+	Hs
		1070503 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		ITSN1_HUMAN (137-479): 1.57e-45: 172: 14.37
+	Hs
		1070670 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		ITSN2_HUMAN (127-483): 1.25e-43: 167: 10.67
+	Hs
		1070626 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		REN3A_HUMAN (44-476): 5.15e-44: 163: 40.05
+	Hs
		1328753 RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38		REN3A_HUMAN (44-476): 5.15e-44: 163: 40.05
+	Hs
		1246388 PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73		THOC2_HUMAN (140-477): 1.26e-34: 140: 13.31