HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: SNX7 (Q9UNH6)
Sorting nexin-7
Gene: SNX7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Hs			1 387
+	Hs
		1081649 NTRK3_HUMAN (1-839): 0: 671: 100.00		SNX6_HUMAN (25-376): 3.02e-63: 209: 16.15
+	Hs
		240327 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38
+	Hs
		384801 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61
+	Hs
		240342 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38
+	Hs
		385804 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		SNX9_HUMAN (28-373): 4e-78: 253: 16.34
+	Hs
		507986 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61
+	Hs
		240351 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38
+	Hs
		508266 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		SNX6_HUMAN (25-376): 3.02e-63: 209: 16.15
+	Hs
		609637 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		SNX11_HUMAN (48-147): 1.97e-09: 59.7: 31.00
+	Hs
		434311 RET_HUMAN (282-837): 1.5e-108: 360: 25.76		SNX6_HUMAN (25-376): 3.02e-63: 209: 16.15
+	Hs
		240332 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38
+	Hs
		240333 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		SNX2_HUMAN (3-378): 7.54e-94: 292: 21.38
+	Hs
		411380 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61
+	Hs
		435636 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		SNX1_HUMAN (1-377): 2.49e-85: 270: 19.61
+	Mm
		1141340 IGF1R_MOUSE (513-820): 9.56e-64: 235: 38.34		SNX9_MOUSE (28-373): 5.95e-81: 260: 16.90
+	Hs
		411539 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		SNX5_HUMAN (29-376): 1.85e-67: 220: 18.42
+	Hs
		435813 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		SNX5_HUMAN (29-376): 1.85e-67: 220: 18.42
+	Hs
		411527 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		SNX6_HUMAN (25-376): 3.02e-63: 209: 16.15
+	Hs
		307875 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		SNX4_HUMAN (31-377): 3.74e-62: 208: 21.61
+	Hs
		435805 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		SNX6_HUMAN (25-376): 3.02e-63: 209: 16.15