HitPredict

Interactor 1: U1SBP (Q16560)
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)
Gene: SNRNP35

Interactor 2: ZCRB1 (Q8TBF4)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K)
Gene: ZCRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm GO:0005689 - U12-type spliceosomal complex GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 217
+	Hs
		442329 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		ZCRB1_HUMAN (1-217): 1.57e-56: 180: 100.00
+	At
		1247086 U1135_ARATH (8-246): 5.1e-42: 147: 42.48		Q8RWF8_ARATH (7-167): 1.58e-32: 121: 20.86
+	Hs
		442193 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		SRSF7_HUMAN (9-120): 7.54e-35: 125: 32.17
+	Hs
		441901 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		CSTF2_HUMAN (10-132): 3.67e-31: 121: 23.39
+	Hs
		442150 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		CIRBP_HUMAN (5-86): 4.16e-30: 111: 32.93
+	Hs
		1119141 PAP1L_HUMAN (4-202): 8.96e-27: 110: 13.74		PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54
+	Hs
		474021 PABP4_HUMAN (4-207): 4.03e-26: 108: 13.60		PAB4L_HUMAN (3-177): 2.05e-39: 140: 20.11
+	Hs
		442125 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		PABP4_HUMAN (11-196): 1.86e-23: 99.6: 12.37
+	Hs
		441852 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10
+	Hs
		442070 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		RBM3_HUMAN (5-91): 1.58e-24: 96.3: 29.89
+	Hs
		441896 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		TIA1_HUMAN (3-125): 1.72e-18: 84.3: 18.70
+	Hs
		442076 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		TIAR_HUMAN (3-142): 1.74e-18: 84.3: 14.89
+	Hs
		442455 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		RBM4_HUMAN (11-103): 1.52e-18: 84.2: 21.51
+	Mm
		857334 RU17_MOUSE (36-135): 1.54e-38: 141: 45.10		TIA1_MOUSE (3-125): 7.02e-18: 82.7: 17.89
+	Hs
		442178 RU17_HUMAN (36-135): 1.04e-38: 141: 45.10		SF3B4_HUMAN (101-215): 5.02e-12: 66.1: 9.84
+	Hs
		516495 PABP4_HUMAN (4-207): 4.03e-26: 108: 13.60		PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10
+	Hs
		516339 PABP1_HUMAN (4-229): 4.07e-25: 105: 13.58		PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10
+	Hs
		1073605 PPIL4_HUMAN (23-129): 1.95e-32: 125: 34.58		SF3B4_HUMAN (101-215): 5.02e-12: 66.1: 9.84
+	Hs
		516471 PABP1_HUMAN (4-229): 4.07e-25: 105: 13.58		TIAR_HUMAN (3-142): 1.74e-18: 84.3: 14.89
+	Mm
		665745 PABP1_MOUSE (4-229): 4.89e-25: 105: 13.58		TIA1_MOUSE (3-125): 7.02e-18: 82.7: 17.89