Protein: TMPSD
Transmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease)

Gene: TMPSD, TMPRSS13
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q9BYE2

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

249059

NRP2
Neuropilin-2

1

20

High-throughput

0.691

High

269884

IGSF3
Immunoglobulin superfamily member 3

1

5

High-throughput

0.691

High

286785

SKAP2
Src kinase-associated phosphoprotein 2

1

3

High-throughput

0.691

High

366552

TPA
Tissue-type plasminogen activator

1

16

High-throughput

0.691

High

376541

LDLR
Low-density lipoprotein receptor

1

11

High-throughput

0.691

High

599130

CBPE
Carboxypeptidase E

1

6

High-throughput

0.691

High

1064073

MFGM
Lactadherin

1

14

High-throughput

0.691

High

1144659

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

8

High-throughput

0.691

High

1249738

SE6L2
Seizure 6-like protein 2

1

5

High-throughput

0.691

High

1249982

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

12

High-throughput

0.691

High

1278318

LRP10
Low-density lipoprotein receptor-related protein 10

1

15

High-throughput

0.691

High

1291960

LRP11
Low-density lipoprotein receptor-related protein 11

1

7

High-throughput

0.691

High

1366773

NECT2
Nectin-2

1

15

High-throughput

0.691

High

1399563

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

1

20

High-throughput

0.691

High

1418356

FPRP
Prostaglandin F2 receptor negative regulator

1

8

High-throughput

0.691

High

1418367

LRP12
Low-density lipoprotein receptor-related protein 12

1

12

High-throughput

0.691

High

215727

COCH
Cochlin

1

4

High-throughput

0.618

High

787837

PEDF
Pigment epithelium-derived factor

1

20

High-throughput

0.618

High

1402421

HPLN3
Hyaluronan and proteoglycan link protein 3

1

5

High-throughput

0.618

High

1418363

PCOC2
Procollagen C-endopeptidase enhancer 2

1

16

High-throughput

0.618

High

1418360

LIMD1
LIM domain-containing protein 1

2

0

High-throughput

0.576

High

452113

PROS
Vitamin K-dependent protein S

1

20

High-throughput

0.575

High

895465

SPB8
Serpin B8

1

20

High-throughput

0.575

High

1209622

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.546

High

160758

TOR1A
Torsin-1A

1

14

High-throughput

0.536

High

161080

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

19

High-throughput

0.536

High

251160

B4GT4
Beta-1,4-galactosyltransferase 4

1

9

High-throughput

0.536

High

261655

CATL2
Cathepsin L2

1

3

High-throughput

0.536

High

283718

GPC4
Glypican-4

1

12

High-throughput

0.536

High

320035

UFL1
E3 UFM1-protein ligase 1

1

5

High-throughput

0.536

High

321036

SUN1
SUN domain-containing protein 1

1

2

High-throughput

0.536

High

459334

CATL1
Procathepsin L

1

3

High-throughput

0.536

High

473718

ITA5
Integrin alpha-5

1

11

High-throughput

0.536

High

582399

B4GT1
Beta-1,4-galactosyltransferase 1

1

9

High-throughput

0.536

High

687129

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

4

High-throughput

0.536

High

755420

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

7

High-throughput

0.536

High

820542

IL6RB
Interleukin-6 receptor subunit beta

1

6

High-throughput

0.536

High

880671

LMAN1
Protein ERGIC-53

1

6

High-throughput

0.536

High

914556

EFNA5
Ephrin-A5

1

4

High-throughput

0.536

High

931989

EPHB4
Ephrin type-B receptor 4

1

18

High-throughput

0.536

High

1038208

GCNT1
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

1

2

High-throughput

0.536

High

1041645

TGBR3
Transforming growth factor beta receptor type 3

1

7

High-throughput

0.536

High

1067038

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

1

High-throughput

0.536

High

1083081

MGAT2
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

1

High-throughput

0.536

High

1083146

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

14

High-throughput

0.536

High

1102751

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

8

High-throughput

0.536

High

1105772

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

18

High-throughput

0.536

High

1116974

CD166
CD166 antigen

1

5

High-throughput

0.536

High

1143669

NOMO1
BOS complex subunit NOMO1

1

5

High-throughput

0.536

High

1286297

GALT7
N-acetylgalactosaminyltransferase 7

1

14

High-throughput

0.536

High

1293290

LSR
Lipolysis-stimulated lipoprotein receptor

1

2

High-throughput

0.536

High

1323091

GPC2
Glypican-2 [Cleaved into: Secreted glypican-2]

1

12

High-throughput

0.536

High

1330382

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.536

High

1372143

EXT2
Exostosin-2

1

4

High-throughput

0.536

High

1394790

CK5P3
CDK5 regulatory subunit-associated protein 3

1

3

High-throughput

0.536

High

1411640

ADPGK
ADP-dependent glucokinase

1

3

High-throughput

0.536

High

1413896

LMF2
Lipase maturation factor 2

1

2

High-throughput

0.536

High

1418028

FUT8
Alpha-(1,6)-fucosyltransferase

1

1

High-throughput

0.536

High

1418344

GL8D2
Glycosyltransferase 8 domain-containing protein 2

1

2

High-throughput

0.536

High

1418348

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

7

High-throughput

0.536

High

1418350

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

11

High-throughput

0.536

High

1418358

DNJB9
DnaJ homolog subfamily B member 9

1

9

High-throughput

0.536

High

1418359

B4GT7
Beta-1,4-galactosyltransferase 7

1

9

High-throughput

0.536

High

1418362

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

12

High-throughput

0.536

High

1418364

CCPG1
Cell cycle progression protein 1

1

1

High-throughput

0.536

High

1418369

GPC6
Glypican-6 [Cleaved into: Secreted glypican-6]

1

12

High-throughput

0.536

High

181656

CETN3
Centrin-3

1

0

High-throughput

0.513

High

1120645

DAG1
Dystroglycan 1

1

0

High-throughput

0.513

High

1358470

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.513

High

1382879

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.513

High

1406717

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

1418351

GINM1
Glycoprotein integral membrane protein 1

1

0

High-throughput

0.513

High

1418354

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

0

High-throughput

0.513

High

212091

B4GT5
Beta-1,4-galactosyltransferase 5

1

9

High-throughput

0.489

High

302265

STC2
Stanniocalcin-2

1

5

High-throughput

0.489

High

324035

CSTN1
Calsyntenin-1

1

11

High-throughput

0.489

High

774801

TIMP3
Metalloproteinase inhibitor 3

1

6

High-throughput

0.489

High

945911

INHBE
Inhibin beta E chain

1

7

High-throughput

0.489

High

999555

NOMO3
BOS complex subunit NOMO3

1

5

High-throughput

0.489

High

1157391

EXT1
Exostosin-1

1

4

High-throughput

0.489

High

1208460

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

2

High-throughput

0.489

High

1217319

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

1

2

High-throughput

0.489

High

1288101

OAF
Out at first protein homolog

1

2

High-throughput

0.489

High

1294933

ERO1B
ERO1-like protein beta

1

2

High-throughput

0.489

High

1325631

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

1

14

High-throughput

0.489

High

1333654

PGLT1
Protein O-glucosyltransferase 1

1

3

High-throughput

0.489

High

1389751

C1GLC
C1GALT1-specific chaperone 1

1

11

High-throughput

0.489

High

1394650

TXD15
Thioredoxin domain-containing protein 15

1

4

High-throughput

0.489

High

1418345

TOR3A
Torsin-3A

1

14

High-throughput

0.489

High

1418346

SIA7D
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase

1

6

High-throughput

0.489

High

1418347

SG196
Protein O-mannose kinase

1

1

High-throughput

0.489

High

1418349

SPON1
Spondin-1

1

5

High-throughput

0.489

High

1418353

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

4

High-throughput

0.489

High

1418357

EXTL2
Exostosin-like 2

1

4

High-throughput

0.489

High

1418361

SUN2
SUN domain-containing protein 2

1

2

High-throughput

0.489

High

1418365

PPT2
Lysosomal thioesterase PPT2

1

1

High-throughput

0.489

High

231165

AIRE
Autoimmune regulator

1

3

High-throughput

0.479

High

331288

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

935094

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

974958

TYB4
Thymosin beta-4

1

0

High-throughput

0.458

High

1340659

NEDD1
Protein NEDD1

1

0

High-throughput

0.458

High

530335

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

535494

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.445

High

699078

CALX
Calnexin

1

13

High-throughput

0.445

High

1090899

TRAF2
TNF receptor-associated factor 2

1

2

High-throughput

0.445

High

1107473

BIRC2
Baculoviral IAP repeat-containing protein 2

1

7

High-throughput

0.445

High

1228401

SE1L3
Protein sel-1 homolog 3

1

2

High-throughput

0.445

High

1418343

LMA2L
VIP36-like protein

1

6

High-throughput

0.445

High

1418368

PCDBB
Protocadherin beta-11

1

2

High-throughput

0.445

High

138300

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.437

High

1401793

OXLA
L-amino-acid oxidase

1

1

Small-scale

0.437

High

1418352

POTE1
Protection of telomeres protein 1

1

1

High-throughput

0.437

High

1381452

PMEPA
Protein TMEPAI

1

0

High-throughput

0.426

High

322164

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

1322721

F177A
Protein FAM177A1

1

0

High-throughput

0.279

Low

1418366

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

0

High-throughput

0.279

Low

1124

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

87535

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

1418355

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025