HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30196744
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Hs			1 607
+	Hs
		997765 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1074793 TAF5_HUMAN (1-255): 1.65e-36: 143: 17.31		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Mm
		1141966 RBBP7_MOUSE (1-425): 3.19e-115: 345: 99.77		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Dm
		1358845 WDS_DROME (212-422): 1.48e-43: 157: 19.91		WDS_DROME (279-565): 1.49e-87: 278: 18.27
+	Hs
		792935 LIS1_HUMAN (8-257): 7.41e-58: 196: 12.77		LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98
+	Mm
		925836 LIS1_MOUSE (8-257): 4.86e-58: 197: 12.77		LIS1_MOUSE (99-438): 1.81e-49: 179: 14.98
+	Hs
		1346954 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34
+	Hs
		921751 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62
+	Hs
		792967 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98
+	Hs
		792949 LIS1_HUMAN (8-257): 7.41e-58: 196: 12.77		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		903349 WDR5B_HUMAN (1-254): 1.38e-58: 196: 14.83		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Mm
		921089 RACK1_MOUSE (213-405): 2.23e-28: 115: 20.41		GBB1_MOUSE (165-516): 5.41e-43: 159: 17.18
+	Mm
		1141943 RBBP4_MOUSE (1-209): 1.59e-39: 148: 12.72		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Mm
		1207553 TAF5_MOUSE (1-255): 1.56e-36: 143: 17.69		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		903551 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		903171 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Mm
		932627 RACK1_MOUSE (213-405): 2.23e-28: 115: 20.41		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		1240442 POC1B_HUMAN (2-170): 4.68e-36: 139: 9.77		POC1A_HUMAN (188-352): 4.31e-16: 82.8: 13.98
+	Hs
		903109 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		301490 POC1B_HUMAN (2-170): 4.68e-36: 139: 9.77		WDR47_HUMAN (315-396): 1.12e-10: 66.7: 22.62