HitPredict

Interactor 1: C3AR (Q16581)
C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R)
Gene: C3AR1

Interactor 2: AT2B3 (Q16720)
Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)
Gene: ATP2B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 1220
+	Hs
		619236 C3AR_HUMAN (1-482): 1.62e-98: 306: 100.00		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		626520 FPR2_HUMAN (316-472): 7.93e-40: 148: 30.91		AT2B3_HUMAN (1-1220): 0: 1287: 100.00
+	Hs
		600763 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		AT2B3_HUMAN (1-1220): 0: 1287: 100.00
+	Hs
		895636 CXCR4_HUMAN (322-457): 2.26e-36: 139: 23.78		AT2B3_HUMAN (1-1220): 0: 1287: 100.00
+	Hs
		626513 FPR2_HUMAN (316-472): 7.93e-40: 148: 30.91		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		600755 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		895608 CXCR4_HUMAN (322-457): 2.26e-36: 139: 23.78		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		588539 FPR2_HUMAN (316-472): 7.93e-40: 148: 30.91		AT2B1_HUMAN (1-1220): 0: 1207: 78.94
+	Hs
		619196 FPR2_HUMAN (316-472): 7.93e-40: 148: 30.91		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		600741 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		588555 CCR2_HUMAN (337-454): 4.23e-35: 136: 28.69		AT2B1_HUMAN (1-1220): 0: 1207: 78.94
+	Hs
		436891 ACM4_HUMAN (2-461): 9.67e-69: 229: 16.50		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		530825 ACM3_HUMAN (2-454): 7.67e-65: 221: 17.59		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		445768 ACM5_HUMAN (4-462): 1.59e-65: 221: 15.90		AT2A2_HUMAN (50-1075): 0: 750: 24.20
+	Hs
		626569 FPR2_HUMAN (316-472): 7.93e-40: 148: 30.91		AT2A3_HUMAN (51-1061): 0: 773: 25.28
+	Hs
		600816 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		AT2A3_HUMAN (51-1061): 0: 773: 25.28
+	Hs
		530832 FPR2_HUMAN (316-472): 7.93e-40: 148: 30.91		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		530988 C5AR2_HUMAN (20-183): 1.06e-39: 148: 39.16		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		530829 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		530862 CXCR4_HUMAN (322-457): 2.26e-36: 139: 23.78		AT1A3_HUMAN (39-1073): 0: 756: 23.47