HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27545878
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 1072
+	Hs
		516636 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		312615 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		ARI2_HUMAN (654-1044): 9.03e-91: 301: 15.84
+	Hs
		302333 SC31A_HUMAN (127-488): 4.72e-28: 121: 14.25		ARI1_HUMAN (600-1058): 1.52e-114: 367: 13.84
+	Hs
		312519 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		ARI2_HUMAN (654-1044): 9.03e-91: 301: 15.84
+	Hs
		1031383 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		CUL9_HUMAN (622-1043): 1.8e-86: 309: 16.09
+	Hs
		312462 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		ARI2_HUMAN (654-1044): 9.03e-91: 301: 15.84
+	Hs
		1084653 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		312672 OGFR_HUMAN (170-417): 4.4e-09: 61.1: 21.76		ARI2_HUMAN (654-1044): 9.03e-91: 301: 15.84
+	Hs
		1235829 CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		847107 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		1031486 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		302330 SC31A_HUMAN (127-488): 4.72e-28: 121: 14.25		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		1329987 PABP3_HUMAN (82-518): 1.28e-22: 103: 15.56		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		1127340 TGO1_HUMAN (138-380): 8.27e-13: 73.8: 25.18		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		867141 SC24C_HUMAN (233-440): 1.79e-12: 72.2: 17.05		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		1312008 DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		1319420 WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		1349442 OGFR_HUMAN (170-417): 4.4e-09: 61.1: 21.76		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44