Protein: PUF3
mRNA-binding protein PUF3 (Pumilio homology domain family member 3)

Gene: PUF3
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: Q07807

Gene Ontology (top 5):
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003729 - mRNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

709478

HRR25
Casein kinase I homolog HRR25

3

1

Small-scale

0.679

High

710014

BMH1
Protein BMH1

2

6

High-throughput

0.611

High

726247

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

2

4

Small-scale

0.611

High

486520

TBA3
Tubulin alpha-3 chain

2

2

High-throughput

0.588

High

805644

LSM12
Protein LSM12

2

1

High-throughput

0.588

High

813311

FHP
Flavohemoprotein

2

1

High-throughput

0.588

High

721668

RENT1
ATP-dependent helicase NAM7

2

6

Small-scale

0.586

High

812127

DHH1
ATP-dependent RNA helicase DHH1

2

11

Small-scale

0.584

High

741149

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

12

High-throughput

0.541

High

403674

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

8

High-throughput

0.536

High

546494

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.536

High

722302

XPO1
Exportin-1

1

8

High-throughput

0.536

High

1030588

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

1060077

MDM12
Mitochondrial distribution and morphology protein 12

1

0

Small-scale

0.529

High

576998

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.513

High

739112

PT309
Mitochondrial COX1 translation regulator PET309

1

0

High-throughput

0.513

High

1038511

RPM2
Ribonuclease P protein component, mitochondrial

1

0

High-throughput

0.513

High

1054973

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.513

High

518144

SSBP1
Single-stranded nucleic acid-binding protein

1

11

High-throughput

0.501

High

743298

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.493

High

918402

FMP48
Probable serine/threonine-protein kinase FMP48

1

1

High-throughput

0.489

High

1042385

GCN5
Histone acetyltransferase GCN5

1

4

High-throughput

0.489

High

1060073

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

5

High-throughput

0.489

High

393425

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

510862

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.479

High

525329

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.479

High

574610

YAK1
Dual specificity protein kinase YAK1

1

6

Small-scale

0.479

High

576013

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

727358

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

748076

SMY2
Protein SMY2

1

4

High-throughput

0.479

High

760366

BMH2
Protein BMH2

1

6

High-throughput

0.479

High

785983

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

809066

POP2
Poly(A) ribonuclease POP2

1

9

Small-scale

0.479

High

919443

PBP1
PAB1-binding protein 1

1

2

Small-scale

0.479

High

925095

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

963757

H3
Histone H3

1

6

High-throughput

0.479

High

1044310

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

1059364

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

1060071

SGO1
Shugoshin

1

1

High-throughput

0.479

High

1060072

RIO1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

1060075

CMR1
DNA damage-binding protein CMR1

1

4

High-throughput

0.479

High

1060076

DCP1
mRNA-decapping enzyme subunit 1

1

1

Small-scale

0.479

High

632118

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.458

High

797799

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

1027376

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.458

High

386882

TBB
Tubulin beta chain

1

1

High-throughput

0.445

High

394947

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.445

High

427460

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.445

High

453822

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.445

High

592535

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

819947

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

824570

6P21
6-phosphofructo-2-kinase 1

1

3

High-throughput

0.445

High

836923

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.445

High

382380

H4
Histone H4

1

1

High-throughput

0.437

High

708344

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

812707

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

826883

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

844635

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

850226

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

5

High-throughput

0.437

High

1053984

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

3

High-throughput

0.437

High

736144

ARP2
Actin-related protein 2

2

0

Small-scale

0.318

High

807279

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.279

Low

1046626

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

383007

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

764019

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

764164

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

795240

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

917275

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.249

Low

1025053

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

1055563

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

1060074

COX17
Cytochrome c oxidase copper chaperone

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025