HitPredict

Interactor 1: MK06 (Q16659)
Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
Gene: MAPK6

Interactor 2: DIC (Q9UBX3)
Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10)
Gene: SLC25A10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26972000, 32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 721 Hs			1 287
+	Hs
		397403 MK06_HUMAN (1-721): 0: 638: 100.00		ADT2_HUMAN (94-281): 1.4e-35: 131: 19.00
+	Hs
		973932 MK06_HUMAN (1-721): 0: 638: 100.00		M2OM_HUMAN (91-281): 3.11e-34: 128: 21.11
+	Hs
		1085538 MK06_HUMAN (1-721): 0: 638: 100.00		S2513_HUMAN (10-102): 8.09e-20: 91: 21.65
+	Hs
		678583 MK04_HUMAN (1-575): 2.49e-137: 418: 52.55		DIC_HUMAN (1-287): 2.49e-93: 279: 100.00
+	Hs
		658973 MK01_HUMAN (8-354): 5.92e-137: 408: 41.83		SCMC2_HUMAN (2-284): 2.23e-90: 277: 20.48
+	Hs
		647610 MK03_HUMAN (8-360): 7.75e-133: 399: 41.41		SCMC2_HUMAN (2-284): 2.23e-90: 277: 20.48
+	Rn
		600394 MK03_RAT (10-362): 7.43e-133: 399: 41.13		ADT1_RAT (93-281): 9.1e-37: 134: 18.41
+	Rn
		600395 MK03_RAT (10-362): 7.43e-133: 399: 41.13		ADT2_RAT (94-281): 9.28e-36: 131: 19.00
+	Hs
		518087 CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19		ADT1_HUMAN (93-281): 6.62e-36: 131: 18.91
+	Hs
		397368 MK07_HUMAN (14-358): 4.26e-121: 383: 38.29		ADT2_HUMAN (94-281): 1.4e-35: 131: 19.00
+	Hs
		518132 MK07_HUMAN (14-358): 4.26e-121: 383: 38.29		ADT1_HUMAN (93-281): 6.62e-36: 131: 18.91
+	Hs
		518334 MK07_HUMAN (14-358): 4.26e-121: 383: 38.29		ADT3_HUMAN (94-281): 1.12e-35: 131: 18.50
+	Hs
		659041 MK01_HUMAN (8-354): 5.92e-137: 408: 41.83		SCMC3_HUMAN (189-280): 1.03e-13: 72.9: 16.84
+	Hs
		647671 MK03_HUMAN (8-360): 7.75e-133: 399: 41.41		SCMC3_HUMAN (189-280): 1.03e-13: 72.9: 16.84