Protein: FOXC2
Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14)

Gene: FOXC2
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q99958

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1091147

FOXC1
Forkhead box protein C1

1

18

High-throughput

0.691

High

1408304

FOXC2
Forkhead box protein C2

1

18

High-throughput

0.691

High

991090

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

2

15

Small-scale

0.611

High

572162

TRI27
Zinc finger protein RFP

1

3

High-throughput

0.573

High

1372051

RBPMS
RNA-binding protein with multiple splicing

1

5

High-throughput

0.573

High

1063568

GOGA2
Golgin subfamily A member 2

2

5

High-throughput

0.553

High

1408305

KRA33
Keratin-associated protein 3-3

2

3

High-throughput

0.553

High

177474

ZN536
Zinc finger protein 536

1

3

High-throughput

0.536

High

229071

AKAP8
A-kinase anchor protein 8

1

5

High-throughput

0.536

High

243716

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.536

High

478914

PO2F2
POU domain, class 2, transcription factor 2

1

20

High-throughput

0.536

High

522833

COT1
COUP transcription factor 1

1

20

High-throughput

0.536

High

576259

PO2F1
POU domain, class 2, transcription factor 1

1

19

High-throughput

0.536

High

593198

CREB1
Cyclic AMP-responsive element-binding protein 1

1

5

High-throughput

0.536

High

604855

HXB9
Homeobox protein Hox-B9

1

20

High-throughput

0.536

High

717960

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

14

High-throughput

0.536

High

725187

HXC13
Homeobox protein Hox-C13

1

20

High-throughput

0.536

High

771605

HXD13
Homeobox protein Hox-D13

1

20

High-throughput

0.536

High

939889

DLX5
Homeobox protein DLX-5

1

20

High-throughput

0.536

High

1032778

SATB1
DNA-binding protein SATB1

1

20

High-throughput

0.536

High

1086298

TFCP2
Alpha-globin transcription factor CP2

1

11

High-throughput

0.536

High

1087976

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.536

High

1217186

RIF1
Telomere-associated protein RIF1

1

10

High-throughput

0.536

High

1335864

ZBT34
Zinc finger and BTB domain-containing protein 34

1

19

High-throughput

0.536

High

1368087

HDAC2
Histone deacetylase 2

1

15

High-throughput

0.536

High

1369123

HXB13
Homeobox protein Hox-B13

1

20

High-throughput

0.536

High

1406444

PITX2
Pituitary homeobox 2

1

19

High-throughput

0.536

High

1408308

SALL1
Sal-like protein 1

1

10

High-throughput

0.536

High

1408310

UBIP1
Upstream-binding protein 1

1

11

High-throughput

0.536

High

1408314

SATB2
DNA-binding protein SATB2

1

20

High-throughput

0.536

High

1290950

TAXB1
Tax1-binding protein 1

1

6

High-throughput

0.523

High

1408309

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.515

High

1394317

Q96IQ6
poly(A)-specific ribonuclease

1

2

High-throughput

0.515

High

1408306

COE3
Transcription factor COE3

1

0

High-throughput

0.513

High

1226724

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

15

High-throughput

0.489

High

1280022

CE024
UPF0461 protein C5orf24

1

1

High-throughput

0.489

High

1408313

CNOT7
CCR4-NOT transcription complex subunit 7

1

2

High-throughput

0.481

High

472122

MET
Hepatocyte growth factor receptor

1

2

Small-scale

0.479

High

1109369

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.479

High

1408311

KDM5B
Lysine-specific demethylase 5B

1

9

Small-scale

0.479

High

1408312

DACH1
Dachshund homolog 1

1

5

High-throughput

0.479

High

284868

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.458

High

1408307

PODO
Podocin

1

6

Small-scale

0.457

High

372967

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.445

High

106548

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

1329269

MET27
Methyltransferase-like protein 27

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025