HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: H2A1J (Q99878)
Histone H2A type 1-J (Histone H2A/e)
Gene: H2AC14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 128
+	Hs
		935170 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2A1J_HUMAN (1-128): 1.15e-67: 201: 100.00
+	Hs
		1086278 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2A1H_HUMAN (1-128): 2.98e-67: 200: 99.22
+	Hs
		391649 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2A1B_HUMAN (1-128): 1.31e-66: 199: 97.66
+	Hs
		470336 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2A1_HUMAN (1-128): 8.92e-67: 199: 99.22
+	Hs
		934877 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2A2A_HUMAN (1-128): 6.49e-67: 199: 97.66
+	Hs
		934946 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2A2B_HUMAN (1-128): 1.05e-66: 199: 95.31
+	Hs
		935141 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2A1A_HUMAN (1-125): 1.01e-66: 199: 95.20
+	Hs
		1086182 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2A2A_HUMAN (1-128): 6.49e-67: 199: 97.66
+	Hs
		1086192 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2A3_HUMAN (1-128): 9.73e-67: 199: 96.88
+	Hs
		1086203 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2A2B_HUMAN (1-128): 1.05e-66: 199: 95.31
+	Hs
		391723 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2A1B_HUMAN (1-128): 1.31e-66: 199: 97.66
+	Hs
		470399 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2A1_HUMAN (1-128): 8.92e-67: 199: 99.22
+	Hs
		391655 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		H2A1B_HUMAN (1-128): 1.31e-66: 199: 97.66
+	Hs
		470350 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		H2A1_HUMAN (1-128): 8.92e-67: 199: 99.22
+	Hs
		934815 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2A2C_HUMAN (1-125): 3.22e-65: 195: 97.60
+	Mm
		935458 H31_MOUSE (1-136): 6.88e-62: 187: 97.06		Q8CGP4_MOUSE (1-126): 3.11e-65: 195: 89.68
+	Hs
		1086165 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2A2C_HUMAN (1-125): 3.22e-65: 195: 97.60
+	Mm
		952759 H33_MOUSE (1-136): 4.53e-61: 185: 93.38		Q8CGP4_MOUSE (1-126): 3.11e-65: 195: 89.68
+	Hs
		555411 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		H2AX_HUMAN (1-124): 1.23e-63: 192: 94.36
+	Hs
		555485 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		H2AX_HUMAN (1-124): 1.23e-63: 192: 94.36