HitPredict

Interactor 1: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.730

The method score is based on:

Property Details
Experiments 16287863, 17403670, 33306668, 37258580, 23091007, 23643811
Identification Methods affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0008284 - positive regulation of cell population proliferation
and 9 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 499
Hs

1 496
+ Dm
+ Sp
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025