Protein: STX11
Syntaxin-11

Gene: STX11
Organism: Homo sapiens
Interactions: 173
UniProt ID: O75558

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

286641

STXB1
Syntaxin-binding protein 1

5

20

High-throughput

0.939

High

286656

STXB2
Syntaxin-binding protein 2

5

20

Small-scale

0.919

High

286721

VAMP8
Vesicle-associated membrane protein 8

5

20

Small-scale

0.919

High

286657

VAMP3
Vesicle-associated membrane protein 3

4

20

Small-scale

0.892

High

286642

VAMP2
Vesicle-associated membrane protein 2

3

20

Small-scale

0.866

High

225885

STX6
Syntaxin-6

3

20

High-throughput

0.855

High

286739

STX8
Syntaxin-8

3

20

High-throughput

0.855

High

286603

STX11
Syntaxin-11

2

19

High-throughput

0.815

High

192149

YKT6
Synaptobrevin homolog YKT6

2

20

High-throughput

0.811

High

249805

STX10
Syntaxin-10

2

20

High-throughput

0.811

High

278459

VAMP4
Vesicle-associated membrane protein 4

2

20

High-throughput

0.811

High

286647

STX4
Syntaxin-4

2

19

High-throughput

0.783

High

286659

STX1A
Syntaxin-1A

2

18

High-throughput

0.783

High

286636

SNAA
Alpha-soluble NSF attachment protein

2

20

High-throughput

0.776

High

123952

SNP23
Synaptosomal-associated protein 23

11

20

Small-scale

0.761

High

286640

SNP25
Synaptosomal-associated protein 25

5

20

High-throughput

0.718

High

286669

STXB5
Syntaxin-binding protein 5

4

16

Small-scale

0.691

High

286738

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

3

2

High-throughput

0.675

High

286734

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

20

High-throughput

0.662

High

286722

KIFC3
Kinesin-like protein KIFC3

3

2

High-throughput

0.650

High

286728

DISC1
Disrupted in schizophrenia 1 protein

4

2

High-throughput

0.638

High

286735

TBK1
Serine/threonine-protein kinase TBK1

4

10

High-throughput

0.632

High

286690

CCHCR
Coiled-coil alpha-helical rod protein 1

4

1

High-throughput

0.631

High

137161

EXOC5
Exocyst complex component 5

2

1

High-throughput

0.628

High

286625

ITPI2
Protein ITPRID2

2

1

High-throughput

0.628

High

286631

SCNND
Epithelial sodium channel subunit delta

2

3

High-throughput

0.628

High

286687

EXOC6
Exocyst complex component 6

2

3

High-throughput

0.628

High

286700

EXOC4
Exocyst complex component 4

2

2

High-throughput

0.628

High

286706

REPS1
RalBP1-associated Eps domain-containing protein 1

2

4

High-throughput

0.628

High

286671

PPR18
Phostensin

3

1

High-throughput

0.616

High

286688

ZN417
Zinc finger protein 417

3

2

High-throughput

0.616

High

286697

KAT5
Histone acetyltransferase KAT5

3

1

High-throughput

0.616

High

286713

ZN587
Zinc finger protein 587

3

1

High-throughput

0.616

High

286612

GOSR1
Golgi SNAP receptor complex member 1

2

10

High-throughput

0.611

High

286649

EI2BE
Translation initiation factor eIF2B subunit epsilon

3

3

High-throughput

0.607

High

286695

SHC3
SHC-transforming protein 3

2

6

High-throughput

0.606

High

286743

AXIN2
Axin-2

2

3

High-throughput

0.606

High

274062

ANR17
Ankyrin repeat domain-containing protein 17

3

9

High-throughput

0.604

High

286720

LRRC1
Leucine-rich repeat-containing protein 1

3

4

High-throughput

0.604

High

286699

BORC5
BLOC-1-related complex subunit 5

2

0

High-throughput

0.602

High

286741

EXOC7
Exocyst complex component 7

2

0

High-throughput

0.602

High

286615

SNP29
Synaptosomal-associated protein 29

2

20

High-throughput

0.601

High

286651

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

3

High-throughput

0.601

High

286693

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

12

High-throughput

0.597

High

225506

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

1

High-throughput

0.590

High

286633

VAMP7
Vesicle-associated membrane protein 7

1

20

High-throughput

0.575

High

286715

SNAG
Gamma-soluble NSF attachment protein

1

20

High-throughput

0.575

High

286724

SNAB
Beta-soluble NSF attachment protein

1

20

High-throughput

0.575

High

286611

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

2

2

High-throughput

0.574

High

286648

LIPA1
Liprin-alpha-1

2

5

High-throughput

0.574

High

286661

KIF7
Kinesin-like protein KIF7

2

1

High-throughput

0.574

High

286667

FKB15
FK506-binding protein 15

2

1

High-throughput

0.574

High

286680

ANKH1
Ankyrin repeat and KH domain-containing protein 1

2

9

High-throughput

0.574

High

286731

NDE1
Nuclear distribution protein nudE homolog 1

2

3

High-throughput

0.574

High

286740

PZRN3
E3 ubiquitin-protein ligase PDZRN3

2

5

High-throughput

0.574

High

286663

F161A
Protein FAM161A

1

2

High-throughput

0.573

High

286681

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

2

High-throughput

0.573

High

286725

CARD9
Caspase recruitment domain-containing protein 9

1

5

High-throughput

0.573

High

286607

RNF8
E3 ubiquitin-protein ligase RNF8

2

1

High-throughput

0.553

High

286608

MTCL2
Microtubule cross-linking factor 2

2

6

High-throughput

0.553

High

286622

ZNF19
Zinc finger protein 19

2

3

High-throughput

0.553

High

286628

HXA1
Homeobox protein Hox-A1

2

3

High-throughput

0.553

High

286654

RNPS1
RNA-binding protein with serine-rich domain 1

2

2

High-throughput

0.553

High

286655

TCEA2
Transcription elongation factor A protein 2

2

2

High-throughput

0.553

High

286664

T10IP
Testis-specific protein 10-interacting protein

2

1

High-throughput

0.553

High

286670

DUS29
Dual specificity phosphatase 29

2

1

High-throughput

0.553

High

286677

CDR2L
Cerebellar degeneration-related protein 2-like

2

2

High-throughput

0.553

High

286692

TRI41
E3 ubiquitin-protein ligase TRIM41

2

1

High-throughput

0.553

High

286710

F161B
Protein FAM161B

2

2

High-throughput

0.553

High

286723

SCNM1
Sodium channel modifier 1

2

1

High-throughput

0.553

High

286604

NU155
Nuclear pore complex protein Nup155

2

1

High-throughput

0.549

High

181037

AXIN1
Axin-1

1

3

High-throughput

0.541

High

286711

S38A2
Sodium-coupled neutral amino acid symporter 2

1

4

High-throughput

0.541

High

286668

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

High-throughput

0.536

High

286703

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

20

High-throughput

0.536

High

286733

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

3

High-throughput

0.536

High

163872

NDC80
Kinetochore protein NDC80 homolog

1

10

High-throughput

0.523

High

286629

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.523

High

286637

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.523

High

286660

LONF1
LON peptidase N-terminal domain and RING finger protein 1

1

2

High-throughput

0.523

High

286673

CCBE1
Collagen and calcium-binding EGF domain-containing protein 1

1

1

High-throughput

0.523

High

286674

KCTD9
BTB/POZ domain-containing protein KCTD9

1

4

High-throughput

0.523

High

286684

USBP1
Harmonin-binding protein USHBP1

1

3

High-throughput

0.523

High

286698

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

3

High-throughput

0.523

High

286726

SH24A
SH2 domain-containing protein 4A

1

2

High-throughput

0.523

High

286736

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

9

High-throughput

0.523

High

286737

IKZF3
Zinc finger protein Aiolos

1

2

High-throughput

0.523

High

286682

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.519

High

69431

A8K287
Synaptosomal-associated protein

1

20

High-throughput

0.515

High

286630

DYN2
Dynamin-2

1

1

High-throughput

0.515

High

286650

PAK1
Serine/threonine-protein kinase PAK 1

1

2

High-throughput

0.515

High

286675

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

286744

BACE2
Beta-secretase 2

1

1

High-throughput

0.515

High

286686

STXB6
Syntaxin-binding protein 6

1

5

High-throughput

0.514

High

286719

NFIP1
NEDD4 family-interacting protein 1

1

0

High-throughput

0.513

High

216356

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

1

High-throughput

0.508

High

284493

TNR21
Tumor necrosis factor receptor superfamily member 21

1

4

High-throughput

0.508

High

286619

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

169353

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

19

High-throughput

0.494

High

286606

CCNK
Cyclin-K

1

4

High-throughput

0.494

High

286623

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.494

High

286624

PSA3
Proteasome subunit alpha type-3

1

3

High-throughput

0.494

High

286702

COQA1
Collagen alpha-1(XXVI) chain

1

0

High-throughput

0.493

High

286609

UBR5
E3 ubiquitin-protein ligase UBR5

1

2

High-throughput

0.489

High

286627

PCY1A
Choline-phosphate cytidylyltransferase A

1

2

High-throughput

0.489

High

286643

CDR2
Cerebellar degeneration-related protein 2

1

2

High-throughput

0.489

High

286626

SYUA
Alpha-synuclein

1

4

High-throughput

0.481

High

160666

TOR1A
Torsin-1A

1

3

High-throughput

0.470

High

167203

KLF11
Krueppel-like factor 11

1

7

High-throughput

0.470

High

274406

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.470

High

286616

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.470

High

286617

CRYAA
Alpha-crystallin A chain

1

2

High-throughput

0.470

High

286646

GOG8D
Putative golgin subfamily A member 8D

1

7

High-throughput

0.470

High

286666

GLE1
mRNA export factor GLE1

1

1

High-throughput

0.470

High

286676

Q86V38
Atrophin 1

1

2

High-throughput

0.470

High

286696

KLK6
Kallikrein-6

1

1

High-throughput

0.470

High

246348

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.464

High

3336

A0A0S2Z4M1
Axin-1

1

3

High-throughput

0.457

High

286638

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.439

High

286742

RNF6
E3 ubiquitin-protein ligase RNF6

1

6

High-throughput

0.439

High

286746

NEMO
NF-kappa-B essential modulator

1

7

High-throughput

0.439

High

286653

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.437

High

286683

CD177
CD177 antigen

1

0

Small-scale

0.426

High

3299

A0A0S2Z4G9
Ring finger protein 6 isoform 2

1

1

High-throughput

0.417

High

249540

SNX3
Sorting nexin-3

1

6

High-throughput

0.417

High

286620

ZN250
Zinc finger protein 250

1

2

High-throughput

0.417

High

96845

E9PCW1
Golgi SNAP receptor complex member 1

1

10

High-throughput

0.407

High

96870

E9PDP5
Ankyrin repeat and KH domain containing 1

1

9

High-throughput

0.407

High

286635

PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein

1

3

High-throughput

0.407

High

286718

SIKE1
Suppressor of IKBKE 1

4

0

High-throughput

0.364

High

286645

TLE5
TLE family member 5

3

0

High-throughput

0.352

High

286652

BYST
Bystin

3

0

High-throughput

0.352

High

286665

CC184
Coiled-coil domain-containing protein 184

3

0

High-throughput

0.352

High

286685

EIF1A
Probable RNA-binding protein EIF1AD

3

0

High-throughput

0.352

High

286730

AIRIM
AFG2-interacting ribosome maturation factor

3

0

High-throughput

0.352

High

284426

HSBP1
Heat shock factor-binding protein 1

2

0

High-throughput

0.328

High

286691

BRK1
Protein BRICK1

2

0

High-throughput

0.328

High

284774

TADA3
Transcriptional adapter 3

2

0

High-throughput

0.316

High

286605

RA51D
DNA repair protein RAD51 homolog 4

2

0

High-throughput

0.316

High

286614

K2C75
Keratin, type II cytoskeletal 75

2

0

High-throughput

0.316

High

286639

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

0

High-throughput

0.316

High

286658

PKN1
Serine/threonine-protein kinase N1

2

0

High-throughput

0.316

High

286679

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.316

High

286694

MB3L1
Methyl-CpG-binding domain protein 3-like 1

2

0

High-throughput

0.316

High

286701

MGN2
Protein mago nashi homolog 2

2

0

High-throughput

0.316

High

286709

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

286714

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.316

High

286732

MS18A
Protein Mis18-alpha

2

0

High-throughput

0.316

High

286689

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.303

High

286613

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.299

High

286621

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

286634

CRBA4
Beta-crystallin A4

1

0

High-throughput

0.299

High

286644

MTG8
Protein CBFA2T1

1

0

High-throughput

0.299

High

286662

C19L2
CWF19-like protein 2

1

0

High-throughput

0.299

High

286672

KLC3
Kinesin light chain 3

1

0

High-throughput

0.299

High

286678

F90A1
Protein FAM90A1

1

0

High-throughput

0.299

High

286704

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.299

High

286705

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.299

High

286707

CDA7L
Cell division cycle-associated 7-like protein

1

0

High-throughput

0.299

High

286708

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.299

High

286716

F110A
Protein FAM110A

1

0

High-throughput

0.299

High

286729

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.299

High

286717

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.282

High

286745

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.282

High

286610

RCBT2
RCC1 and BTB domain-containing protein 2

1

0

High-throughput

0.279

Low

4769

A0A1B0GWI1
Coiled-coil domain containing 196

1

0

High-throughput

0.268

Low

47290

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

167549

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.268

Low

286632

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.268

Low

286618

TTHY
Transthyretin

1

0

High-throughput

0.232

Low

286712

WRIP1
ATPase WRNIP1

1

0

High-throughput

0.232

Low

286727

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025