HitPredict

Interactor 1: RHG44 (Q17R89)
Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2)
Gene: ARHGAP44

Interactor 2: FBP1L (Q5T0N5)
Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1)
Gene: FNBP1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 818 Hs			1 605
+	Hs
		1075786 RHG44_HUMAN (1-818): 1.01e-156: 479: 100.00		CIP4_HUMAN (1-599): 1.04e-94: 304: 50.58
+	Hs
		1148383 RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34		FNBP1_HUMAN (1-605): 1.1e-101: 323: 53.96
+	Hs
		1075791 RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34		CIP4_HUMAN (1-599): 1.04e-94: 304: 50.58
+	Hs
		1075823 3BP1_HUMAN (1-589): 2.97e-86: 290: 39.22		CIP4_HUMAN (1-599): 1.04e-94: 304: 50.58
+	Dm
		112686 RG92B_DROME (1-735): 6.75e-82: 279: 22.91		M9NE16_DROME (1-597): 2.58e-87: 285: 30.45
+	Hs
		1075787 Q1RLN5_HUMAN (49-434): 8.75e-68: 242: 19.80		CIP4_HUMAN (1-599): 1.04e-94: 304: 50.58
+	Hs
		253304 SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15		SRG2C_HUMAN (6-397): 1.53e-68: 231: 14.48
+	Hs
		253374 SRGP1_HUMAN (12-751): 2.95e-75: 267: 15.13		SRGP2_HUMAN (6-445): 4.29e-58: 212: 13.67
+	Hs
		200194 SRGP3_HUMAN (12-710): 4.72e-73: 261: 14.75		SRGP3_HUMAN (5-448): 7.41e-59: 215: 14.26
+	Hs
		200200 SRGP3_HUMAN (12-710): 4.72e-73: 261: 14.75		SRGP2_HUMAN (6-445): 4.29e-58: 212: 13.67
+	Hs
		253290 SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15		SRGP2_HUMAN (6-445): 4.29e-58: 212: 13.67
+	Hs
		1148385 RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34		PACN1_HUMAN (187-595): 2.32e-18: 89.9: 11.86
+	Hs
		957808 RHG04_HUMAN (108-683): 2.32e-71: 254: 17.63		RHG04_HUMAN (1-452): 2.73e-57: 209: 14.55
+	Hs
		200232 SH3G2_HUMAN (1-251): 1.54e-73: 245: 21.43		SRGP3_HUMAN (5-448): 7.41e-59: 215: 14.26
+	Hs
		200223 RHG24_HUMAN (150-610): 2.07e-67: 240: 17.95		SRGP3_HUMAN (5-448): 7.41e-59: 215: 14.26
+	Hs
		561401 RHG23_HUMAN (243-762): 1.53e-67: 246: 20.37		FER_HUMAN (1-464): 9.42e-54: 198: 12.42
+	Hs
		561393 RHG21_HUMAN (102-734): 7.8e-67: 244: 17.73		FER_HUMAN (1-464): 9.42e-54: 198: 12.42
+	Hs
		1357492 3BP1_HUMAN (1-589): 2.97e-86: 290: 39.22		PACN2_HUMAN (303-595): 6.96e-20: 94.9: 12.50