Interactor 1: DERL2 (Q21997)
Derlin-2 (DER1-like protein 2) (cDerlin-2)
Gene: R151.6

Interactor 2: DERL1 (Q93561)
Derlin-1 (Coelomocyte uptake defective protein 2) (DER1-like protein 1) (cDerlin-1)
Gene: cup-2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 21722281
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DER1~DER1
Common GO terms GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005047 - signal recognition particle binding
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0036503 - ERAD pathway
GO:0051787 - misfolded protein binding
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 237
Ce

1 245
+ Hs
+ Ce
+ Ce
+ Hs
+ At
+ At
+ At
+ Sc
+ Sc
+ Sc
+ Sp

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Last updated: 15 Jul 2024