HitPredict

Interactor 1: CNKR2 (Q80YA9)
Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)
Gene: Cnksr2

Interactor 2: DLGP1 (Q9D415)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: Dlgap1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0045211 - postsynaptic membrane GO:0098978 - glutamatergic synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1032 Mm			1 992
+	Mm
		1206880 CNKR3_MOUSE (5-500): 0: 574: 56.60		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Mm
		956467 MPRIP_MOUSE (354-1029): 6.11e-62: 231: 16.24		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Rn
		291496 MAGI2_RAT (221-958): 5.83e-14: 79: 11.30		DLGP1_RAT (1-992): 0: 1344: 98.49
+	Hs
		145951 MAGI2_HUMAN (196-524): 5.74e-09: 62.4: 13.17		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Hs
		1136441 MAGI3_HUMAN (200-788): 2.71e-72: 265: 13.63		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Rn
		291497 MAGI2_RAT (221-958): 5.83e-14: 79: 11.30		DLGP2_RAT (1-992): 0: 1067: 50.34
+	Hs
		1199792 MAGI2_HUMAN (196-524): 5.74e-09: 62.4: 13.17		DLGP2_HUMAN (1-992): 0: 1081: 51.69
+	Rn
		291499 MAGI2_RAT (221-958): 5.83e-14: 79: 11.30		DLGP4_RAT (1-992): 0: 1027: 45.88
+	Hs
		327243 MAGI2_HUMAN (196-524): 5.74e-09: 62.4: 13.17		DLGP3_HUMAN (1-992): 0: 986: 37.16
+	Rn
		291498 MAGI2_RAT (221-958): 5.83e-14: 79: 11.30		DLGP3_RAT (1-992): 0: 968: 37.85
+	Hs
		1153633 MAGI2_HUMAN (196-524): 5.74e-09: 62.4: 13.17		Q6IS01_HUMAN (1-539): 0: 809: 93.88