Protein: UBP37
Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37)

Gene: UBP37, USP37
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q86T82

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1287028

FBW1B
F-box/WD repeat-containing protein 11

8

11

Small-scale

0.965

High

508216

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

6

20

Small-scale

0.948

High

1287033

FBW1A
F-box/WD repeat-containing protein 1A

5

7

Small-scale

0.931

High

1286989

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

2

17

Small-scale

0.768

High

1287030

FZR1
Fizzy-related protein homolog

6

5

Small-scale

0.729

High

350058

SNAI1
Zinc finger protein SNAI1

3

10

Small-scale

0.683

High

1138356

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

Small-scale

0.618

High

1250010

WDR82
WD repeat-containing protein 82

1

11

Small-scale

0.618

High

1287002

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

6

Small-scale

0.618

High

667919

CDK2
Cyclin-dependent kinase 2

2

7

Small-scale

0.595

High

718589

CDC27
Cell division cycle protein 27 homolog

2

7

Small-scale

0.584

High

992237

SKP1
S-phase kinase-associated protein 1

2

2

Small-scale

0.584

High

1287024

APC7
Anaphase-promoting complex subunit 7

2

6

Small-scale

0.584

High

372444

MYC
Myc proto-oncogene protein

1

12

Small-scale

0.578

High

926372

BLM
RecQ-like DNA helicase BLM

1

12

Small-scale

0.578

High

1240647

CDC73
Parafibromin

1

2

Small-scale

0.573

High

163128

CHK1
Serine/threonine-protein kinase Chk1

1

1

Small-scale

0.561

High

396422

ESR1
Estrogen receptor

1

14

Small-scale

0.561

High

629138

CCNA2
Cyclin-A2

1

4

Small-scale

0.561

High

966548

1433G
14-3-3 protein gamma

1

20

Small-scale

0.561

High

1287015

CDT1
DNA replication factor Cdt1

2

0

Small-scale

0.559

High

1287025

APC5
Anaphase-promoting complex subunit 5

2

0

Small-scale

0.559

High

390085

ALBU
Albumin

1

2

High-throughput

0.536

High

1287021

KRT84
Keratin, type II cuticular Hb4

1

6

High-throughput

0.536

High

1286993

STAG2
Cohesin subunit SA-2

1

1

Small-scale

0.515

High

1287032

SMC3
Structural maintenance of chromosomes protein 3

1

5

Small-scale

0.515

High

1102199

ATM
Serine-protein kinase ATM

1

10

Small-scale

0.501

High

1270880

RHOU
Rho-related GTP-binding protein RhoU

1

5

High-throughput

0.501

High

1287004

AURKB
Aurora kinase B

1

18

Small-scale

0.501

High

238550

RAD21
Double-strand-break repair protein rad21 homolog

1

0

Small-scale

0.493

High

1279187

WAPL
Wings apart-like protein homolog

1

0

Small-scale

0.493

High

134786

SAP18
Histone deacetylase complex subunit SAP18

1

1

Small-scale

0.479

High

170217

AURKA
Aurora kinase A

1

18

Small-scale

0.479

High

180863

TIF1A
Transcription intermediary factor 1-alpha

1

20

Small-scale

0.479

High

207574

DHX15
ATP-dependent RNA helicase DHX15

1

4

Small-scale

0.479

High

272836

PHF2
Lysine-specific demethylase PHF2

1

3

Small-scale

0.479

High

274347

SIN3B
Paired amphipathic helix protein Sin3b

1

1

Small-scale

0.479

High

289597

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

13

Small-scale

0.479

High

291940

WDHD1
WD repeat and HMG-box DNA-binding protein 1

1

8

Small-scale

0.479

High

462493

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

5

Small-scale

0.479

High

466679

GLI1
Zinc finger protein GLI1

1

2

Small-scale

0.479

High

502035

H2AZ
Histone H2A.Z

1

15

Small-scale

0.479

High

551129

PCNA
Proliferating cell nuclear antigen

1

3

Small-scale

0.479

High

573852

CCNB1
G2/mitotic-specific cyclin-B1

1

4

Small-scale

0.479

High

589045

RFA2
Replication protein A 32 kDa subunit

1

3

Small-scale

0.479

High

639767

TAF1
Transcription initiation factor TFIID subunit 1

1

16

Small-scale

0.479

High

695834

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

Small-scale

0.479

High

755747

MCM4
DNA replication licensing factor MCM4

1

10

Small-scale

0.479

High

764868

CTNB1
Catenin beta-1

1

15

Small-scale

0.479

High

768545

RFA3
Replication protein A 14 kDa subunit

1

4

Small-scale

0.479

High

799252

BRCA1
Breast cancer type 1 susceptibility protein

1

20

Small-scale

0.479

High

838749

MTREX
Exosome RNA helicase MTR4

1

9

Small-scale

0.479

High

857488

NOTC1
Neurogenic locus notch homolog protein 1

1

9

Small-scale

0.479

High

892044

TAF6
Transcription initiation factor TFIID subunit 6

1

4

Small-scale

0.479

High

909612

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

9

Small-scale

0.479

High

920080

PLK1
Serine/threonine-protein kinase PLK1

1

17

Small-scale

0.479

High

938373

NH2L1
NHP2-like protein 1

1

4

Small-scale

0.479

High

959610

MAX
Protein max

1

12

Small-scale

0.479

High

968360

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

3

Small-scale

0.479

High

1005901

GTF2I
General transcription factor II-I

1

1

Small-scale

0.479

High

1054478

EXOS9
Exosome complex component RRP45

1

1

Small-scale

0.479

High

1086874

CDC20
Cell division cycle protein 20 homolog

1

6

Small-scale

0.479

High

1092575

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

3

Small-scale

0.479

High

1092991

CDC16
Cell division cycle protein 16 homolog

1

7

Small-scale

0.479

High

1097392

CBX3
Chromobox protein homolog 3

1

11

Small-scale

0.479

High

1109851

HDAC1
Histone deacetylase 1

1

11

Small-scale

0.479

High

1112575

CUL1
Cullin-1

1

16

Small-scale

0.479

High

1128232

MCM6
DNA replication licensing factor MCM6

1

11

Small-scale

0.479

High

1130091

SMC1A
Structural maintenance of chromosomes protein 1A

1

5

Small-scale

0.479

High

1145252

RNPS1
RNA-binding protein with serine-rich domain 1

1

8

Small-scale

0.479

High

1217143

RIF1
Telomere-associated protein RIF1

1

4

Small-scale

0.479

High

1235644

NIPBL
Nipped-B-like protein

1

7

Small-scale

0.479

High

1259312

TBA1A
Tubulin alpha-1A chain

1

7

Small-scale

0.479

High

1277168

POGZ
Pogo transposable element with ZNF domain

1

1

Small-scale

0.479

High

1286990

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

3

Small-scale

0.479

High

1286991

SUGP2
SURP and G-patch domain-containing protein 2

1

1

Small-scale

0.479

High

1286992

CCAR2
Cell cycle and apoptosis regulator protein 2

1

4

Small-scale

0.479

High

1286994

Z280C
Zinc finger protein 280C

1

1

Small-scale

0.479

High

1286996

STAG1
Cohesin subunit SA-1

1

1

Small-scale

0.479

High

1286999

HDAC2
Histone deacetylase 2

1

11

Small-scale

0.479

High

1287003

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

8

Small-scale

0.479

High

1287005

IPO9
Importin-9

1

2

Small-scale

0.479

High

1287006

WRIP1
ATPase WRNIP1

1

5

Small-scale

0.479

High

1287007

MINT
Msx2-interacting protein

1

7

Small-scale

0.479

High

1287008

EPAS1
Endothelial PAS domain-containing protein 1

1

14

Small-scale

0.479

High

1287010

SF3B5
Splicing factor 3B subunit 5

1

1

Small-scale

0.479

High

1287011

FANCJ
Fanconi anemia group J protein

1

1

Small-scale

0.479

High

1287012

DPY30
Protein dpy-30 homolog

1

1

Small-scale

0.479

High

1287013

TRIM4
E3 ubiquitin-protein ligase TRIM4

1

20

Small-scale

0.479

High

1287014

APC1
Anaphase-promoting complex subunit 1

1

1

Small-scale

0.479

High

1287017

PININ
Pinin

1

3

Small-scale

0.479

High

1287018

TAF9B
Transcription initiation factor TFIID subunit 9B

1

6

Small-scale

0.479

High

1287019

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

2

Small-scale

0.479

High

1287020

METL5
rRNA N(6)-adenosine-methyltransferase METTL5

1

1

Small-scale

0.479

High

1287022

MS18A
Protein Mis18-alpha

1

1

Small-scale

0.479

High

1287023

CDC23
Cell division cycle protein 23 homolog

1

7

Small-scale

0.479

High

1287029

TF3C4
General transcription factor 3C polypeptide 4

1

1

Small-scale

0.479

High

1287031

PRP19
Pre-mRNA-processing factor 19

1

7

Small-scale

0.479

High

1287035

TF3C3
General transcription factor 3C polypeptide 3

1

2

Small-scale

0.479

High

885588

PRI2
DNA primase large subunit

1

0

Small-scale

0.458

High

912081

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

Small-scale

0.458

High

948549

APC15
Anaphase-promoting complex subunit 15

1

0

Small-scale

0.458

High

1203563

ZN326
DBIRD complex subunit ZNF326

1

0

Small-scale

0.458

High

1272234

MCM10
Protein MCM10 homolog

1

0

Small-scale

0.458

High

1286995

CDC26
Anaphase-promoting complex subunit CDC26

1

0

Small-scale

0.458

High

1286997

PHF3
PHD finger protein 3

1

0

Small-scale

0.458

High

1287000

INT12
Integrator complex subunit 12

1

0

Small-scale

0.458

High

1287001

APC16
Anaphase-promoting complex subunit 16

1

0

Small-scale

0.458

High

1287009

APC13
Anaphase-promoting complex subunit 13

1

0

Small-scale

0.458

High

1287016

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

Small-scale

0.458

High

1287026

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

1287027

TASOR
Protein TASOR

1

0

Small-scale

0.458

High

1287034

PAXB1
PAX3- and PAX7-binding protein 1

1

0

Small-scale

0.458

High

680412

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

7

High-throughput

0.437

High

1286998

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.437

High


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Last updated: 11Aug2025