HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: NBEL2 (Q6ZNJ1)
Neurobeachin-like protein 2
Gene: NBEAL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	29187380
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 414 Hs			1 2754
+	Hs
		909606 ROA3_HUMAN (98-269): 2.35e-69: 225: 28.57		NBEL2_HUMAN (1-2754): 0: 2880: 100.00
+	Hs
		1101998 PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92		NBEL2_HUMAN (1-2754): 0: 2880: 100.00
+	Hs
		1120211 HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93		NBEL2_HUMAN (1-2754): 0: 2880: 100.00
+	Hs
		964908 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		WDR5_HUMAN (2586-2753): 7.45e-41: 157: 8.72
+	Hs
		172055 HNRDL_HUMAN (62-376): 5.65e-71: 231: 23.60		WDR5_HUMAN (2586-2753): 7.45e-41: 157: 8.72
+	Hs
		909520 ROA3_HUMAN (98-269): 2.35e-69: 225: 28.57		WDR5_HUMAN (2586-2753): 7.45e-41: 157: 8.72
+	Hs
		992723 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		RACK1_HUMAN (2590-2751): 4.48e-20: 95.7: 14.02
+	Hs
		909648 ROA3_HUMAN (98-269): 2.35e-69: 225: 28.57		FBXW7_HUMAN (2358-2525): 1.59e-20: 101: 13.64
+	Hs
		964916 PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92		WDR5_HUMAN (2586-2753): 7.45e-41: 157: 8.72
+	Dm
		198197 Q9W1I0_DROME (4-323): 9.26e-62: 204: 48.77		GBLP_DROME (2540-2751): 1.97e-20: 96.9: 11.63
+	Dm
		198153 Q8SXP8_DROME (4-389): 1.82e-58: 201: 44.70		GBLP_DROME (2540-2751): 1.97e-20: 96.9: 11.63
+	Hs
		964936 HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93		WDR5_HUMAN (2586-2753): 7.45e-41: 157: 8.72
+	Hs
		992729 PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92		RACK1_HUMAN (2590-2751): 4.48e-20: 95.7: 14.02
+	Hs
		550204 PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62		WDR5_HUMAN (2586-2753): 7.45e-41: 157: 8.72
+	Hs
		1120277 HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93		FBXW7_HUMAN (2358-2525): 1.59e-20: 101: 13.64
+	Dm
		198148 Q8IMS8_DROME (106-263): 7.47e-21: 96.7: 35.76		GBLP_DROME (2540-2751): 1.97e-20: 96.9: 11.63
+	Dm
		198168 Q9VBQ1_DROME (106-263): 1.16e-20: 96.3: 35.76		GBLP_DROME (2540-2751): 1.97e-20: 96.9: 11.63
+	Hs
		992741 HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93		RACK1_HUMAN (2590-2751): 4.48e-20: 95.7: 14.02
+	Hs
		550219 PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62		RACK1_HUMAN (2590-2751): 4.48e-20: 95.7: 14.02
+	Mm
		97567 PABP1_MOUSE (181-270): 3.15e-10: 64: 20.62		E9PV60_MOUSE (2651-2752): 3.4e-11: 71.8: 13.76