HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: TBA8 (Q9NY65)
Tubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
Gene: TUBA8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29715546
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 449
+	Hs
		1096191 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		TBA1C_HUMAN (1-449): 0: 717: 89.76
+	Hs
		996676 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		457404 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		909608 ROA3_HUMAN (98-269): 2.35e-69: 225: 28.57		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Dm
		1174637 Q9W1I0_DROME (4-323): 9.26e-62: 204: 48.77		TBB1_DROME (1-439): 0: 690: 38.95
+	Dm
		1174591 Q8SXP8_DROME (4-389): 1.82e-58: 201: 44.70		TBB1_DROME (1-439): 0: 690: 38.95
+	Hs
		94451 D6RBZ0_HUMAN (94-269): 2.41e-20: 92.8: 30.60		TBA1A_HUMAN (1-439): 0: 704: 90.89