HitPredict

Interactor 1: DYIN (Q24246)
Cytoplasmic dynein 1 intermediate chain (DH IC) (Dynein intermediate chain, cytosolic) (Protein short wing)
Gene: sw

Interactor 2: DYLT (Q94524)
Dynein light chain Tctex-type (TCTEX-1 protein homolog)
Gene: Dlc90F

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	11914076, 17428790, 16949604
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Dynein_IC2~Tctex-1
Common GO terms	GO:0005868 - cytoplasmic dynein complex GO:0005874 - microtubule GO:0007018 - microtubule-based movement GO:0032991 - protein-containing complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 663 Dm			1 111
+	Hs
		148060 DC1I1_HUMAN (2-661): 9.6e-111: 349: 46.34		DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30
+	Hs
		148055 DC1I1_HUMAN (2-661): 9.6e-111: 349: 46.34		DYLT3_HUMAN (6-111): 2.38e-43: 138: 48.11
+	Hs
		928590 DC1I2_HUMAN (2-661): 1.59e-107: 340: 46.46		DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30
+	Hs
		850528 DC1I2_HUMAN (2-661): 1.59e-107: 340: 46.46		DYLT3_HUMAN (6-111): 2.38e-43: 138: 48.11
+	Hs
		928656 DC2I2_HUMAN (224-657): 6.56e-93: 299: 21.70		DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30
+	Cr
		65480 A8IJZ3_CHLRE (169-649): 2.88e-99: 316: 20.83		O04355_CHLRE (8-109): 1.08e-35: 120: 23.30
+	Hs
		1262253 DC2I2_HUMAN (224-657): 6.56e-93: 299: 21.70		DYT2B_HUMAN (1-108): 8.69e-37: 123: 23.85
+	Hs
		1127237 DC2I2_HUMAN (224-657): 6.56e-93: 299: 21.70		DYLT4_HUMAN (29-109): 6.05e-26: 97.8: 23.17
+	Hs
		792965 LIS1_HUMAN (498-650): 8.7e-33: 133: 15.69		DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30
+	Hs
		792944 LIS1_HUMAN (498-650): 8.7e-33: 133: 15.69		DYLT3_HUMAN (6-111): 2.38e-43: 138: 48.11
+	Hs
		928646 DC2I1_HUMAN (309-654): 1.12e-27: 121: 19.91		DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30
+	Hs
		793018 LIS1_HUMAN (498-650): 8.7e-33: 133: 15.69		DYT2B_HUMAN (1-108): 8.69e-37: 123: 23.85
+	Hs
		1261757 DC2I1_HUMAN (309-654): 1.12e-27: 121: 19.91		DYT2B_HUMAN (1-108): 8.69e-37: 123: 23.85
+	Hs
		1127235 DC2I1_HUMAN (309-654): 1.12e-27: 121: 19.91		DYLT4_HUMAN (29-109): 6.05e-26: 97.8: 23.17