Interactor 1: CUL1 (Q24311)
Cullin homolog 1 (Lin-19 homolog protein)
Gene: CUL1
Interactor 2: RBX1A (Q9W5E1)
RING-box protein 1A (Regulator of cullins 1a) (dRbx1)
Gene: Roc1a
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.74 | 1.00 | 0.861 |
The method score is based on:
Property | Details |
---|---|
Experiments | 23747190, 18698375, 15331761, unassigned4 |
Identification Methods | affinity chromatography technology, experimental interaction detection |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1 |
Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process and 4 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024