HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: Z280C (Q8ND82)
Zinc finger protein 280C (Suppressor of hairy wing homolog 3) (Zinc finger protein 633)
Gene: ZNF280C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	27705803, 34079125, 32296183, 33961781, unassigned1304
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 737
+	Hs
		70557 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (70-736): 0: 592: 11.70
+	Hs
		1097355 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		Z280D_HUMAN (3-732): 0: 563: 66.98
+	Mm
		1229292 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		Z280D_MOUSE (1-732): 0: 558: 61.98
+	Hs
		1097517 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN184_HUMAN (350-737): 1.61e-159: 481: 14.52
+	Hs
		67023 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (72-628): 8.49e-136: 433: 13.19
+	Hs
		776911 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF93_HUMAN (323-737): 5.64e-142: 432: 15.33
+	Hs
		1056668 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN33A_HUMAN (72-552): 2.07e-137: 426: 11.98
+	Hs
		1097385 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		POGZ_HUMAN (58-720): 4.14e-112: 371: 33.79
+	Hs
		1097401 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN227_HUMAN (322-737): 5.03e-110: 354: 12.81
+	Hs
		1097595 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN226_HUMAN (431-737): 3.91e-92: 306: 11.11
+	Hs
		1097425 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN615_HUMAN (481-734): 1.06e-67: 239: 9.78
+	Hs
		1097324 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN568_HUMAN (382-730): 2.23e-63: 225: 13.85
+	Hs
		1097442 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (535-737): 2.36e-51: 192: 10.22
+	Hs
		1051147 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (70-339): 4.89e-42: 167: 8.19
+	Hs
		1097489 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN333_HUMAN (236-471): 1.06e-23: 108: 17.37
+	Hs
		1097574 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN287_HUMAN (167-345): 8.49e-23: 106: 10.24
+	Hs
		1097597 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		RBAK_HUMAN (71-300): 1.99e-22: 104: 8.71
+	Hs
		65255 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN316_HUMAN (239-433): 1.43e-15: 83.1: 17.44
+	Hs
		1097449 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN480_HUMAN (531-730): 1.85e-15: 81.9: 12.45
+	Hs
		1097501 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN570_HUMAN (530-728): 5.84e-12: 70.7: 13.70