HitPredict

Interactor 1: VWC2 (Q2TAL6)
Brorin (Brain-specific chordin-like protein) (von Willebrand factor C domain-containing protein 2)
Gene: VWC2

Interactor 2: KRA24 (Q9BYR9)
Keratin-associated protein 2-4 (High sulfur keratin-associated protein 2.4) (Keratin-associated protein 2.4)
Gene: KRTAP2-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 128
+	Hs
		473284 VWC2_HUMAN (1-325): 1.71e-79: 246: 100.00		KRA23_HUMAN (1-128): 5.59e-24: 90.9: 100.00
+	Hs
		889490 VWC2_HUMAN (1-325): 1.71e-79: 246: 100.00		KR108_HUMAN (3-128): 2.67e-17: 76.7: 24.03
+	Hs
		70759 VWC2L_HUMAN (137-323): 5.38e-30: 115: 57.75		KR108_HUMAN (3-128): 2.67e-17: 76.7: 24.03
+	Hs
		1317251 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KRA93_HUMAN (5-126): 9.27e-27: 99: 26.15
+	Hs
		1216392 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KRA13_HUMAN (2-128): 4.29e-22: 87.5: 21.83
+	Hs
		889684 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR108_HUMAN (3-128): 2.67e-17: 76.7: 24.03
+	Hs
		889125 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR105_HUMAN (3-128): 3.54e-15: 71.3: 20.67
+	Hs
		888620 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR123_HUMAN (41-128): 7.9e-16: 69.3: 25.84
+	Hs
		1317336 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KRA42_HUMAN (3-99): 2.57e-14: 66.3: 39.39
+	Hs
		889892 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR109_HUMAN (3-109): 1.13e-12: 64.7: 32.52
+	Hs
		887427 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR122_HUMAN (41-127): 1.52e-11: 59.3: 21.84
+	Hs
		888996 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR103_HUMAN (2-114): 1.49e-10: 58.2: 21.60
+	Hs
		888777 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR101_HUMAN (37-128): 6.58e-10: 57: 27.72
+	Hs
		889399 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR107_HUMAN (23-128): 7.2e-10: 57: 23.68
+	Hs
		991669 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KRA11_HUMAN (44-128): 2.15e-10: 57: 27.91
+	Hs
		1317277 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KRA92_HUMAN (2-104): 1.16e-09: 55.1: 23.31
+	Hs
		887339 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR121_HUMAN (1-99): 6.79e-10: 53.9: 27.27
+	Hs
		1309019 CHRD_HUMAN (32-277): 2.1e-13: 73: 19.57		KR412_HUMAN (1-119): 9.73e-09: 52.8: 28.46