Protein: STRAP
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)

Gene: STRAP
Organism: Homo sapiens
Interactions: 224
UniProt ID: Q9Y3F4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000387 - spliceosomal snRNP assembly
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1459962

DDX20
Probable ATP-dependent RNA helicase DDX20

5

20

High-throughput

0.927

High

1353069

GEMI5
Gem-associated protein 5

3

20

High-throughput

0.871

High

1491236

STRAP
Serine-threonine kinase receptor-associated protein

2

17

Small-scale

0.776

High

1160627

SMN
Survival motor neuron protein

8

1

Small-scale

0.754

High

286313

CSDE1
Cold shock domain-containing protein E1

8

2

High-throughput

0.749

High

1360316

GEMI6
Gem-associated protein 6

6

0

Small-scale

0.703

High

1436083

GEMI7
Gem-associated protein 7

6

0

Small-scale

0.703

High

1363722

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.691

High

1411788

LARP6
La-related protein 6

3

7

High-throughput

0.667

High

167141

GEMI2
Gem-associated protein 2

4

0

Small-scale

0.664

High

944600

GEMI4
Gem-associated protein 4

4

0

High-throughput

0.664

High

1451593

GEMI8
Gem-associated protein 8

4

0

High-throughput

0.664

High

974701

SMD2
Small nuclear ribonucleoprotein Sm D2

3

2

Small-scale

0.660

High

473213

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

7

High-throughput

0.656

High

787473

TGFR1
TGF-beta receptor type-1

3

3

Small-scale

0.640

High

1067867

EP300
Histone acetyltransferase p300

3

13

Small-scale

0.640

High

155373

CDKA1
Cyclin-dependent kinase 2-associated protein 1

2

2

High-throughput

0.628

High

547226

PYC
Pyruvate carboxylase, mitochondrial

2

13

High-throughput

0.628

High

1150643

TSN
Translin

2

2

High-throughput

0.628

High

1405627

TSNAX
Translin-associated protein X

2

2

High-throughput

0.628

High

1447105

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

3

High-throughput

0.628

High

1454508

ZNFX1
NFX1-type zinc finger-containing protein 1

2

9

High-throughput

0.628

High

844122

HD
Huntingtin

2

2

High-throughput

0.621

High

574529

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

5

Small-scale

0.619

High

141713

DDX3X
ATP-dependent RNA helicase DDX3X

1

12

High-throughput

0.618

High

246193

KIF1B
Kinesin-like protein KIF1B

1

10

High-throughput

0.618

High

316203

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.618

High

869101

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.618

High

883374

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

5

High-throughput

0.618

High

957565

UBC12
NEDD8-conjugating enzyme Ubc12

1

6

High-throughput

0.618

High

971340

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.618

High

1007351

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

1138802

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

7

High-throughput

0.618

High

1155936

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

High-throughput

0.618

High

1256221

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.618

High

1258049

RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1

1

10

High-throughput

0.618

High

1289741

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.618

High

1407643

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.618

High

1428244

ARP6
Actin-related protein 6

1

6

High-throughput

0.618

High

1434305

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.618

High

1447484

ANLN
Anillin

1

5

High-throughput

0.618

High

1454376

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

13

High-throughput

0.618

High

775389

FUS
RNA-binding protein FUS

2

17

High-throughput

0.611

High

974090

RUXF
Small nuclear ribonucleoprotein F

2

13

High-throughput

0.611

High

1370177

RENT1
Regulator of nonsense transcripts 1

2

5

High-throughput

0.611

High

1432613

CK068
UPF0696 protein C11orf68

2

0

High-throughput

0.602

High

564597

CFTR
Cystic fibrosis transmembrane conductance regulator

2

5

High-throughput

0.601

High

891905

GSK3B
Glycogen synthase kinase-3 beta

2

9

Small-scale

0.601

High

584823

NDKA
Nucleoside diphosphate kinase A

1

1

Small-scale

0.600

High

973855

RUXE
Small nuclear ribonucleoprotein E

2

2

Small-scale

0.595

High

181197

AXIN1
Axin-1

1

0

Small-scale

0.586

High

1258427

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.586

High

177734

SMAD7
Mothers against decapentaplegic homolog 7

2

8

Small-scale

0.584

High

243370

PRKN
E3 ubiquitin-protein ligase parkin

2

17

High-throughput

0.584

High

789048

TGFR2
TGF-beta receptor type-2

2

3

Small-scale

0.584

High

1335097

SERB1
SERPINE1 mRNA-binding protein 1

2

3

High-throughput

0.584

High

1142227

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.578

High

91897

C9K0J5
Ras association

1

15

High-throughput

0.575

High

1235046

PKHA7
Pleckstrin homology domain-containing family A member 7

1

17

High-throughput

0.575

High

1217640

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

2

11

High-throughput

0.574

High

401749

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

9

High-throughput

0.571

High

935331

TERA
Transitional endoplasmic reticulum ATPase

2

5

High-throughput

0.571

High

1114725

CUL3
Cullin-3

2

20

High-throughput

0.571

High

1209830

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

10

High-throughput

0.571

High

1370490

CSN5
COP9 signalosome complex subunit 5

2

9

High-throughput

0.571

High

355053

CHK2
Serine/threonine-protein kinase Chk2

1

4

Small-scale

0.550

High

619966

VCAM1
Vascular cell adhesion protein 1

2

5

High-throughput

0.549

High

290219

OFD1
Centriole and centriolar satellite protein OFD1

2

0

High-throughput

0.547

High

214471

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

3

High-throughput

0.536

High

414898

P53
Cellular tumor antigen p53

1

6

High-throughput

0.536

High

478269

SNRPA
U1 small nuclear ribonucleoprotein A

1

9

High-throughput

0.536

High

480362

RU1C
U1 small nuclear ribonucleoprotein C

1

3

High-throughput

0.536

High

484692

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

625725

CSK22
Casein kinase II subunit alpha'

1

13

High-throughput

0.536

High

909256

NEK4
Serine/threonine-protein kinase Nek4

1

9

High-throughput

0.536

High

1116164

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

High-throughput

0.536

High

1270358

SPT6H
Transcription elongation factor SPT6

1

5

High-throughput

0.536

High

1336338

LS14A
Protein LSM14 homolog A

1

7

High-throughput

0.536

High

1347903

RIN3
Ras and Rab interactor 3

1

6

High-throughput

0.536

High

1365704

LAR4B
La-related protein 4B

1

7

High-throughput

0.536

High

1406400

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

6

Small-scale

0.536

High

106902

APRIO
Alternative prion protein

2

3

High-throughput

0.533

High

1145449

RNPS1
RNA-binding protein with serine-rich domain 1

1

10

High-throughput

0.515

High

951918

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

964519

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

974873

SMD3
Small nuclear ribonucleoprotein Sm D3

1

16

Small-scale

0.501

High

226627

TLX2
T-cell leukemia homeobox protein 2

1

7

High-throughput

0.500

High

1057483

SOX4
Transcription factor SOX-4

1

20

High-throughput

0.500

High

1118703

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.500

High

1405752

KLF6
Krueppel-like factor 6

1

19

High-throughput

0.500

High

1340275

PLBL2
Putative phospholipase B-like 2

1

1

High-throughput

0.489

High

129587

MEN1
Menin

1

4

High-throughput

0.479

High

132398

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

Small-scale

0.479

High

173595

XPO1
Exportin-1

1

15

High-throughput

0.479

High

193649

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

5

Small-scale

0.479

High

219883

SMAD6
Mothers against decapentaplegic homolog 6

1

8

Small-scale

0.479

High

226920

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

12

High-throughput

0.479

High

248160

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

254663

EIF1B
Eukaryotic translation initiation factor 1b

1

2

High-throughput

0.479

High

277440

TP4A3
Protein tyrosine phosphatase type IVA 3

1

6

High-throughput

0.479

High

294573

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

302679

RNF8
E3 ubiquitin-protein ligase RNF8

1

8

High-throughput

0.479

High

320179

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

346544

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

11

High-throughput

0.479

High

352610

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.479

High

364073

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

373583

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

380204

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

3

High-throughput

0.479

High

397294

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

406838

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

465059

SP1
Transcription factor Sp1

1

15

Small-scale

0.479

High

485535

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

19

High-throughput

0.479

High

487910

PARP1
Poly [ADP-ribose] polymerase 1

1

8

High-throughput

0.479

High

590104

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

607257

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.479

High

630104

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

648258

NDKB
Nucleoside diphosphate kinase B

1

1

High-throughput

0.479

High

696943

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

718856

CCND2
G1/S-specific cyclin-D2

1

12

Small-scale

0.479

High

731725

STIP1
Stress-induced-phosphoprotein 1

1

12

High-throughput

0.479

High

766043

BMI1
Polycomb complex protein BMI-1

1

18

High-throughput

0.479

High

766970

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

799603

BRCA1
Breast cancer type 1 susceptibility protein

1

11

High-throughput

0.479

High

831695

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

849051

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

2

High-throughput

0.479

High

862576

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.479

High

867546

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.479

High

872924

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

898549

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

900239

FXR1
RNA-binding protein FXR1

1

11

High-throughput

0.479

High

954323

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

959303

ABCE1
ATP-binding cassette sub-family E member 1

1

3

High-throughput

0.479

High

1014671

SMAD3
Mothers against decapentaplegic homolog 3

1

8

Small-scale

0.479

High

1024955

VIGLN
Vigilin

1

16

High-throughput

0.479

High

1026292

CLH1
Clathrin heavy chain 1

1

5

High-throughput

0.479

High

1026603

HSF1
Heat shock factor protein 1

1

4

Small-scale

0.479

High

1057062

FMR1
Fragile X messenger ribonucleoprotein 1

1

11

High-throughput

0.479

High

1089076

TP53B
TP53-binding protein 1

1

5

High-throughput

0.479

High

1092282

NFX1
Transcriptional repressor NF-X1

1

12

High-throughput

0.479

High

1093743

MKRN3
E3 ubiquitin-protein ligase makorin-3

1

1

High-throughput

0.479

High

1101114

G3BP1
Ras GTPase-activating protein-binding protein 1

1

8

High-throughput

0.479

High

1107362

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

High-throughput

0.479

High

1110210

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

1116336

PTC1
Protein patched homolog 1

1

1

Small-scale

0.479

High

1121385

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.479

High

1122597

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

4

High-throughput

0.479

High

1127276

RBM39
RNA-binding protein 39

1

13

High-throughput

0.479

High

1129542

PUM1
Pumilio homolog 1

1

2

High-throughput

0.479

High

1141088

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.479

High

1153954

SMAD2
Mothers against decapentaplegic homolog 2

1

8

Small-scale

0.479

High

1229790

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

1257185

PAXI1
PAX-interacting protein 1

1

16

High-throughput

0.479

High

1275772

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

8

High-throughput

0.479

High

1280627

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.479

High

1333378

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1339769

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1352860

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1363902

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1364315

TOPB1
DNA topoisomerase 2-binding protein 1

1

14

High-throughput

0.479

High

1364725

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1369886

CELF1
CUGBP Elav-like family member 1

1

3

High-throughput

0.479

High

1370264

DAZL
Deleted in azoospermia-like

1

6

High-throughput

0.479

High

1370595

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.479

High

1393864

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1397589

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1403383

RUFY1
RUN and FYVE domain-containing protein 1

1

14

High-throughput

0.479

High

1406815

BARD1
BRCA1-associated RING domain protein 1

1

8

High-throughput

0.479

High

1411773

RIOK1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

1418544

ACE2
Angiotensin-converting enzyme 2

1

2

Small-scale

0.479

High

1429029

WWTR1
WW domain-containing transcription regulator protein 1

1

9

High-throughput

0.479

High

1435716

TDRD3
Tudor domain-containing protein 3

1

2

High-throughput

0.479

High

1436577

ECT2
Protein ECT2

1

14

High-throughput

0.479

High

1438955

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

5

High-throughput

0.479

High

1448341

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

1451334

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

1453139

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

2

High-throughput

0.479

High

1453329

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

14

High-throughput

0.479

High

1458563

HDAC6
Protein deacetylase HDAC6

1

20

High-throughput

0.479

High

1459421

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1461064

TNIK
TRAF2 and NCK-interacting protein kinase

1

10

High-throughput

0.479

High

1461935

FZR1
Fizzy-related protein homolog

1

17

High-throughput

0.479

High

1461970

NOTC3
Neurogenic locus notch homolog protein 3

1

10

Small-scale

0.479

High

1461988

MYO6
Unconventional myosin-VI

1

5

High-throughput

0.479

High

1462749

HDAC5
Histone deacetylase 5

1

20

High-throughput

0.479

High

1491238

TRAF6
TNF receptor-associated factor 6

1

11

High-throughput

0.479

High

1491239

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

14

High-throughput

0.479

High

377237

SOMA
Somatotropin

1

1

High-throughput

0.470

High

716162

PBLD
Phenazine biosynthesis-like domain-containing protein

1

0

Small-scale

0.460

High

261742

HUS1
Checkpoint protein HUS1

1

0

High-throughput

0.458

High

762374

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

762511

PROF2
Profilin-2

1

0

High-throughput

0.458

High

766233

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

1178479

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1218709

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

1361103

BAALC
Brain and acute leukemia cytoplasmic protein

1

0

High-throughput

0.458

High

1400768

UIF
UAP56-interacting factor

1

0

Small-scale

0.458

High

1429412

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.458

High

1431458

MMP28
Matrix metalloproteinase-28

1

0

Small-scale

0.458

High

1491237

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

171622

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

404966

PRIO
Major prion protein

1

1

High-throughput

0.445

High

430550

JUN
Transcription factor Jun

1

14

High-throughput

0.445

High

530643

TAU
Microtubule-associated protein tau

1

17

High-throughput

0.445

High

952388

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.445

High

1108767

TBB3
Tubulin beta-3 chain

1

13

High-throughput

0.445

High

1259593

TBA1A
Tubulin alpha-1A chain

1

10

High-throughput

0.445

High

1291305

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

13

High-throughput

0.445

High

1437430

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.445

High

1453988

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.438

High

218999

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

353643

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

412859

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

769588

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

1452397

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1461721

HECD1
E3 ubiquitin-protein ligase HECTD1

1

17

High-throughput

0.437

High

1491026

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

403048

ANXA1
Annexin A1

1

2

Small-scale

0.408

High

887371

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.408

High

1278012

SZRD1
SUZ RNA-binding domain-containing

7

0

High-throughput

0.389

High

1431023

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

239901

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

1253214

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

1410243

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025