HitPredict

Interactor 1: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Interactor 2: FGF11 (Q92914)
Fibroblast growth factor 11 (FGF-11) (Fibroblast growth factor homologous factor 3) (FHF-3)
Gene: FGF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 225
+	Hs
		1103723 JIP2_HUMAN (1-824): 2.75e-152: 468: 100.00		FGF14_HUMAN (2-225): 2.47e-100: 293: 61.61
+	Hs
		961169 JIP2_HUMAN (1-824): 2.75e-152: 468: 100.00		FGF12_HUMAN (2-225): 1.15e-99: 291: 59.21
+	Hs
		1103721 JIP2_HUMAN (1-824): 2.75e-152: 468: 100.00		FGF13_HUMAN (2-225): 3.84e-99: 289: 58.04
+	Hs
		274217 ANR17_HUMAN (104-457): 1.91e-10: 67.1: 13.63		FGF11_HUMAN (1-225): 9.06e-106: 305: 100.00
+	Hs
		274086 ANR17_HUMAN (104-457): 1.91e-10: 67.1: 13.63		FGF3_HUMAN (50-223): 1.23e-58: 186: 29.03
+	Hs
		240129 ANR17_HUMAN (104-457): 1.91e-10: 67.1: 13.63		FGF17_HUMAN (74-222): 4.6e-47: 156: 23.38
+	Hs
		274125 ANR17_HUMAN (104-457): 1.91e-10: 67.1: 13.63		FGF8_HUMAN (74-224): 7.05e-42: 143: 25.33
+	Hs
		1224917 TENS2_HUMAN (105-502): 5.28e-10: 65.4: 17.16		FGF21_HUMAN (59-188): 2.86e-34: 123: 22.63