Protein: FGF21
Fibroblast growth factor 21 (FGF-21)

Gene: FGF21
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q9NSA1

Gene Ontology (top 5):
GO:0005104 - fibroblast growth factor receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1295752

KLOTB
Beta-klotho

1

1

Small-scale

0.647

High

226891

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

1

High-throughput

0.606

High

1389512

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

2

High-throughput

0.553

High

1224917

TENS2
Tensin-2

2

0

High-throughput

0.551

High

1097168

MK07
Mitogen-activated protein kinase 7

1

1

High-throughput

0.541

High

931131

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.534

High

719182

MPIP1
M-phase inducer phosphatase 1

1

0

High-throughput

0.518

High

856944

BAG6
Large proline-rich protein BAG6

1

6

High-throughput

0.515

High

937120

CASP6
Caspase-6

1

1

High-throughput

0.515

High

861800

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

High-throughput

0.501

High

160015

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

562433

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

167404

KLF11
Krueppel-like factor 11

1

6

High-throughput

0.470

High

1156709

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

Small-scale

0.458

High

1449288

CADH7
Cadherin-7

1

0

High-throughput

0.282

High

1081567

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

959537

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025