Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1
Interactor 2: IKZF2 (Q9UKS7)
Zinc finger protein Helios (Ikaros family zinc finger protein 2)
Gene: IKZF2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.919 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9560339, 28514442, 33961781, 35583604, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | zf-C2H2~zf-C2H2 |
| Common GO terms | GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
