Protein: IKZF5
Zinc finger protein Pegasus (Ikaros family zinc finger protein 5)

Gene: IKZF5
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9H5V7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1104672

IKZF1
DNA-binding protein Ikaros

5

15

Small-scale

0.719

High

1434728

IKZF3
Zinc finger protein Aiolos

4

15

Small-scale

0.698

High

1432144

IKZF4
Zinc finger protein Eos

3

15

Small-scale

0.674

High

1434720

CHD8
Chromodomain-helicase-DNA-binding protein 8

3

20

High-throughput

0.662

High

1434717

IKZF5
Zinc finger protein Pegasus

3

16

Small-scale

0.656

High

573891

CCNB1
G2/mitotic-specific cyclin-B1

3

0

High-throughput

0.634

High

283546

TAD2A
Transcriptional adapter 2-alpha

2

5

High-throughput

0.628

High

284878

TADA3
Transcriptional adapter 3

2

1

High-throughput

0.628

High

345004

WIZ
Protein Wiz

2

16

High-throughput

0.628

High

572215

TRI27
Zinc finger protein RFP

2

17

High-throughput

0.628

High

753933

CKS2
Cyclin-dependent kinases regulatory subunit 2

2

3

High-throughput

0.628

High

1135532

RHG19
Rho GTPase-activating protein 19

2

12

High-throughput

0.628

High

1152742

ELF2
ETS-related transcription factor Elf-2

2

1

High-throughput

0.628

High

1198318

TIGD5
Tigger transposable element-derived protein 5

2

9

High-throughput

0.628

High

1203259

ODFP2
Outer dense fiber protein 2

2

3

High-throughput

0.628

High

1293817

FBX11
F-box only protein 11

2

2

High-throughput

0.628

High

1313147

ZC3H3
Zinc finger CCCH domain-containing protein 3

2

2

High-throughput

0.628

High

1315053

ZZZ3
ZZ-type zinc finger-containing protein 3

2

1

High-throughput

0.628

High

1369159

KAT2A
Histone acetyltransferase KAT2A

2

15

High-throughput

0.628

High

1369208

KAT2B
Histone acetyltransferase KAT2B

2

13

High-throughput

0.628

High

1383735

MIB2
E3 ubiquitin-protein ligase MIB2

2

3

High-throughput

0.628

High

1389074

THA11
THAP domain-containing protein 11

2

1

High-throughput

0.628

High

1420928

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

5

High-throughput

0.628

High

1421079

Z518B
Zinc finger protein 518B

2

19

High-throughput

0.628

High

1434719

CSR2B
Cysteine-rich protein 2-binding protein

2

1

High-throughput

0.628

High

1434721

TF7L2
Transcription factor 7-like 2

2

13

High-throughput

0.628

High

1434724

SLTM
SAFB-like transcription modulator

2

6

High-throughput

0.628

High

1434727

IKZF2
Zinc finger protein Helios

2

14

High-throughput

0.628

High

1434729

YETS2
YEATS domain-containing protein 2

2

10

High-throughput

0.628

High

1380754

RL36L
Ribosomal protein eL42-like

2

5

High-throughput

0.611

High

278964

PEX14
Peroxisomal membrane protein PEX14

2

0

High-throughput

0.602

High

1216488

AHDC1
Transcription factor Gibbin

2

0

High-throughput

0.602

High

1236078

LIN54
Protein lin-54 homolog

2

0

High-throughput

0.602

High

1272260

MCM10
Protein MCM10 homolog

2

0

High-throughput

0.602

High

1389688

SGF29
SAGA-associated factor 29

2

0

High-throughput

0.602

High

1434723

MBIP1
MAP3K12-binding inhibitory protein 1

2

0

High-throughput

0.602

High

956686

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

3

High-throughput

0.574

High

1081612

DYH14
Dynein axonemal heavy chain 14

2

1

High-throughput

0.574

High

1434718

NOL6
Nucleolar protein 6

2

1

High-throughput

0.574

High

1434722

PDLI7
PDZ and LIM domain protein 7

2

3

High-throughput

0.574

High

1434730

UTP11
Probable U3 small nucleolar RNA-associated protein 11

2

1

High-throughput

0.574

High

443520

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.536

High

447444

NPM
Nucleophosmin

1

10

High-throughput

0.536

High

1434725

RBM27
RNA-binding protein 27

1

3

High-throughput

0.536

High

166194

AIM2
Interferon-inducible protein AIM2

1

8

High-throughput

0.489

High

605155

KCRS
Creatine kinase S-type, mitochondrial

1

2

High-throughput

0.489

High

1428624

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

2

High-throughput

0.489

High

297688

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

High-throughput

0.481

High

343806

LDOC1
Protein LDOC1

1

2

High-throughput

0.481

High

993751

UBC9
SUMO-conjugating enzyme UBC9

1

7

High-throughput

0.481

High

714969

EF1D
Elongation factor 1-delta

1

2

High-throughput

0.479

High

887225

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.479

High

1235523

IFIX
Pyrin and HIN domain-containing protein 1

1

8

High-throughput

0.479

High

1401391

CIC
Protein capicua homolog

1

16

High-throughput

0.479

High

1434726

LHX3
LIM/homeobox protein Lhx3

1

20

High-throughput

0.479

High

1154591

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.460

High

1367276

ESR2
Estrogen receptor beta

1

16

High-throughput

0.445

High

1326552

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.426

High

343704

GGPPS
Geranylgeranyl pyrophosphate synthase

2

0

High-throughput

0.328

High

1178013

MOONR
Protein moonraker

2

0

High-throughput

0.328

High

1240400

M18BP
Mis18-binding protein 1

2

0

High-throughput

0.328

High

1349549

RM30
Large ribosomal subunit protein uL30m

2

0

High-throughput

0.328

High

1411046

CCD77
Coiled-coil domain-containing protein 77

2

0

High-throughput

0.328

High

1421211

CEP44
Centrosomal protein of 44 kDa

2

0

High-throughput

0.328

High

1212467

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.279

Low

1411584

NUD22
Uridine diphosphate glucose pyrophosphatase NUDT22

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025