HitPredict

Interactor 1: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23524849
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 305
+	Hs
		1107097 BIRC3_HUMAN (1-604): 0: 676: 100.00		SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42
+	Hs
		964919 BIRC3_HUMAN (1-604): 0: 676: 100.00		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		209260 BIRC3_HUMAN (1-604): 0: 676: 100.00		PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68
+	Hs
		1107337 BIRC3_HUMAN (1-604): 0: 676: 100.00		WDR3_HUMAN (6-218): 4.84e-10: 62.4: 25.56
+	Hs
		1085650 BIRC3_HUMAN (1-604): 0: 676: 100.00		TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93
+	Hs
		1380186 BIRC6_HUMAN (7-136): 3.5e-35: 144: 20.29		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30