HitPredict

Interactor 1: PCGF3 (Q3KNV8)
Polycomb group RING finger protein 3 (RING finger protein 3A)
Gene: PCGF3

Interactor 2: AUTS2 (Q8WXX7)
Autism susceptibility gene 2 protein
Gene: AUTS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	25519132, 27705803, 22325352
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 242 Hs			1 1259
+	Mm
		393 PCGF3_MOUSE (1-242): 1.74e-64: 202: 97.52		AUTS2_MOUSE (1-1259): 7.09e-133: 440: 90.25
+	Hs
		1264229 PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Hs
		1197576 PCGF5_HUMAN (4-241): 3.95e-40: 140: 38.06		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Mm
		1161097 PCGF3_MOUSE (1-242): 1.74e-64: 202: 97.52		Q6PED7_MOUSE (637-1259): 1.68e-63: 230: 92.01
+	Hs
		554277 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		MUC1_HUMAN (21-960): 4.41e-54: 209: 12.26
+	Hs
		1108546 PCGF3_HUMAN (1-242): 8.16e-66: 205: 100.00		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		1108544 PCGF3_HUMAN (1-242): 8.16e-66: 205: 100.00		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		718208 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		718429 PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1316706 PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		1311545 PCGF1_HUMAN (3-238): 1.66e-45: 154: 38.33		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1316704 PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1197591 PCGF5_HUMAN (4-241): 3.95e-40: 140: 38.06		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		718055 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		TITIN_HUMAN (60-591): 1.15e-09: 65.3: 11.92
+	Hs
		585039 RO52_HUMAN (2-241): 3.02e-47: 164: 15.56		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		1223393 TRI22_HUMAN (2-237): 1.71e-43: 155: 16.15		RERE_HUMAN (10-900): 6.62e-13: 75.9: 9.42
+	Hs
		1316711 PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62		RERE_HUMAN (10-900): 6.62e-13: 75.9: 9.42
+	Hs
		1223389 TRI22_HUMAN (2-237): 1.71e-43: 155: 16.15		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		1056961 PCGF1_HUMAN (3-238): 1.66e-45: 154: 38.33		MDC1_HUMAN (700-1257): 7.36e-10: 65.9: 8.20
+	Hs
		1300927 PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34