HitPredict

Interactor 1: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Interactor 2: NPTN (Q9Y639)
Neuroplastin (Stromal cell-derived receptor 1) (SDR-1)
Gene: NPTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007411 - axon guidance GO:0030424 - axon
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 398
+	Hs
		1192021 TBB8_HUMAN (1-427): 0: 705: 87.59		NPTN_HUMAN (1-398): 1.32e-76: 244: 100.00
+	Hs
		774337 TBB3_HUMAN (1-450): 0: 723: 100.00		BASI_HUMAN (10-398): 5.2e-65: 214: 38.58
+	Hs
		774394 TBB8_HUMAN (1-427): 0: 705: 87.59		BASI_HUMAN (10-398): 5.2e-65: 214: 38.58
+	Hs
		457265 TBB5_HUMAN (1-429): 0: 704: 93.94		BASI_HUMAN (10-398): 5.2e-65: 214: 38.58
+	Hs
		774280 TBB4B_HUMAN (1-427): 0: 703: 93.91		BASI_HUMAN (10-398): 5.2e-65: 214: 38.58
+	Hs
		774344 TBB2A_HUMAN (1-430): 0: 699: 93.49		BASI_HUMAN (10-398): 5.2e-65: 214: 38.58
+	Hs
		407993 TBB4A_HUMAN (1-427): 0: 698: 93.21		BASI_HUMAN (10-398): 5.2e-65: 214: 38.58
+	Hs
		1108777 TBB3_HUMAN (1-450): 0: 723: 100.00		ROBO1_HUMAN (2-397): 3.04e-49: 180: 15.79
+	Hs
		408203 TBB4A_HUMAN (1-427): 0: 698: 93.21		ROBO1_HUMAN (2-397): 3.04e-49: 180: 15.79
+	Hs
		1191934 TBB8_HUMAN (1-427): 0: 705: 87.59		LRIG1_HUMAN (228-338): 5.7e-09: 60.3: 18.10
+	Dm
		56150 Q8MST5_DROME (1-447): 0: 690: 86.13		A1Z9X4_DROME (101-326): 3.63e-09: 60.8: 25.52