HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: TLN1 (Q9Y490)
Talin-1
Gene: TLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 2541
+	Mm
		1240039 HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94		TLN2_MOUSE (1-1787): 0: 866: 74.87
+	Hs
		767198 HDAC1_HUMAN (1-482): 0: 668: 100.00		MERL_HUMAN (80-638): 6.05e-90: 308: 14.79
+	Hs
		582779 HDAC1_HUMAN (1-482): 0: 668: 100.00		EZRI_HUMAN (84-666): 3.04e-82: 285: 14.65
+	Hs
		683876 HDAC2_HUMAN (1-478): 0: 666: 85.92		MOES_HUMAN (163-404): 1.94e-51: 195: 23.05
+	Hs
		1109726 HDAC1_HUMAN (1-482): 0: 668: 100.00		GOGB1_HUMAN (243-2541): 1.91e-45: 184: 8.51
+	Hs
		1110043 HDAC1_HUMAN (1-482): 0: 668: 100.00		CP250_HUMAN (353-1871): 3.99e-30: 133: 8.09
+	Hs
		1109744 HDAC1_HUMAN (1-482): 0: 668: 100.00		PLEC_HUMAN (916-2528): 1.86e-24: 115: 11.40
+	Hs
		1110225 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (1762-2538): 2.39e-20: 101: 9.21
+	Hs
		563054 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (1792-2538): 2.47e-19: 98.4: 10.17
+	Hs
		1040284 HDAC1_HUMAN (1-482): 0: 668: 100.00		DYST_HUMAN (372-2531): 7.74e-18: 93.8: 8.71
+	Hs
		556922 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (1889-2532): 5.43e-16: 87.2: 10.32
+	Hs
		1110177 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (2033-2538): 2.32e-10: 68.7: 11.11
+	Hs
		556850 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (2033-2533): 7.85e-10: 67.2: 10.64
+	Mm
		858186 HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94		MERL_MOUSE (80-630): 2e-87: 301: 14.33
+	Mm
		683937 HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94		EZRI_MOUSE (84-708): 5.8e-82: 284: 13.53
+	Mm
		683958 HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94		RADI_MOUSE (163-404): 1.93e-56: 210: 22.27
+	Mm
		683946 HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94		MOES_MOUSE (163-404): 2.52e-51: 194: 23.05
+	Hs
		683905 HDAC6_HUMAN (16-325): 2.06e-93: 309: 25.78		MOES_HUMAN (163-404): 1.94e-51: 195: 23.05
+	Hs
		1132354 HDAC6_HUMAN (16-325): 2.06e-93: 309: 25.78		GOGB1_HUMAN (243-2541): 1.91e-45: 184: 8.51
+	Hs
		1143293 HDAC6_HUMAN (16-325): 2.06e-93: 309: 25.78		PLEC_HUMAN (916-2528): 1.86e-24: 115: 11.40