HitPredict

Interactor 1: FADA5 (I6XHI4)
Steroid 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acetyltransferase FadA5) (Beta-ketoacyl-CoA thiolase)
Gene: FADA5

Interactor 2: FADA5 (I6XHI4)
Steroid 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acetyltransferase FadA5) (Beta-ketoacyl-CoA thiolase)
Gene: FADA5

Species: Mycobacterium tuberculosis H37Rv

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	1.00	0.716

Property	Details
Experiments	25482540
Identification Methods	molecular sieving, light scattering, x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Thiolase_C~Thiolase_C, Thiolase_C~Thiolase_N, Thiolase_N~Thiolase_N
Common GO terms	GO:0003988 - acetyl-CoA C-acyltransferase activity GO:0006635 - fatty acid beta-oxidation GO:0006707 - cholesterol catabolic process GO:0010124 - phenylacetate catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 391 Mt			1 391
+	Hs
		623889 THIL_HUMAN (1-391): 2.28e-157: 451: 32.59		THIL_HUMAN (1-391): 2.28e-157: 451: 32.59
+	Hs
		623985 THIL_HUMAN (1-391): 2.28e-157: 451: 32.59		THIC_HUMAN (4-390): 4.57e-153: 439: 33.67
+	At
		1248131 ACCT2_ARATH (2-389): 6.07e-153: 439: 31.42		ACCT2_ARATH (2-389): 6.07e-153: 439: 31.42
+	Hs
		1314565 THIC_HUMAN (4-390): 4.57e-153: 439: 33.67		THIC_HUMAN (4-390): 4.57e-153: 439: 33.67
+	Sc
		783354 ERG10_YEAST (2-391): 6.15e-152: 436: 30.69		ERG10_YEAST (2-391): 6.15e-152: 436: 30.69
+	Ec
		1115238 YQEF_ECOLI (1-390): 1.4e-151: 435: 37.72		YQEF_ECOLI (1-390): 1.4e-151: 435: 37.72
+	Sc
		653475 THIK_YEAST (2-388): 2.32e-138: 402: 32.49		THIK_YEAST (2-388): 2.32e-138: 402: 32.49