HitPredict

Interactor 1: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Interactor 2: ANS1B (Q8BIZ1)
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1)
Gene: Anks1b

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Ank_2, Ank_2~ArfGap, Ank_2~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1186 Mm			1 1259
+	Mm
		103599 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		ANK3_MOUSE (8-1075): 2.51e-70: 262: 12.20
+	Mm
		1148425 GIT1_MOUSE (932-1139): 6.25e-72: 258: 32.88		ANS1B_MOUSE (1-1259): 0: 938: 100.00
+	Mm
		1112622 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		ANK2_MOUSE (66-258): 3.34e-10: 67: 30.05
+	Mm
		1206695 ASAP1_MOUSE (61-401): 7.43e-09: 62.2: 16.72		ANS1B_MOUSE (1-1259): 0: 938: 100.00
+	Hs
		1335969 AGAP1_HUMAN (384-1145): 0: 713: 53.70		TANC2_HUMAN (104-1028): 3.1e-30: 132: 12.41
+	Hs
		1299062 AGAP3_HUMAN (384-1150): 0: 687: 52.37		TANC2_HUMAN (104-1028): 3.1e-30: 132: 12.41