Interactor 1: NLRC4 (Q3UP24)
NLR family CARD domain-containing protein 4 (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf)
Gene: NLRC4
Interactor 2: ASC (Q9EPB4)
Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein)
Gene: Pycard
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.646 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22885697 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD |
| Common GO terms | GO:0002218 - activation of innate immune response GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0006954 - inflammatory response GO:0032731 - positive regulation of interleukin-1 beta production and 5 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
