HitPredict

Interactor 1: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Interactor 2: ASB4 (Q9Y574)
Ankyrin repeat and SOCS box protein 4 (ASB-4)
Gene: ASB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	33961781, 24337577
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin, Ank_4~Tubulin, Ank_4~Tubulin_C
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 426
+	Hs
		1037456 TBB3_HUMAN (1-442): 0: 719: 86.43		ASB4_HUMAN (1-426): 3.59e-96: 296: 100.00
+	Hs
		1046628 TBB2A_HUMAN (1-430): 0: 715: 90.00		ASB4_HUMAN (1-426): 3.59e-96: 296: 100.00
+	Hs
		428145 TBB5_HUMAN (1-429): 0: 720: 89.74		ANK2_HUMAN (15-407): 1.71e-84: 284: 16.53
+	Hs
		965103 TBB2A_HUMAN (1-430): 0: 715: 90.00		ANK2_HUMAN (15-407): 1.71e-84: 284: 16.53
+	Mm
		57384 TBB5_MOUSE (1-429): 0: 720: 89.74		A2AM57_MOUSE (9-407): 2.46e-61: 216: 15.73
+	Hs
		862023 TBB4B_HUMAN (1-427): 0: 719: 91.10		DAPK1_HUMAN (133-409): 1.92e-47: 176: 14.19
+	Hs
		428113 TBB5_HUMAN (1-429): 0: 720: 89.74		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		428431 TBB5_HUMAN (1-429): 0: 720: 89.74		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		1037393 TBB3_HUMAN (1-442): 0: 719: 86.43		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		1313672 TBB2B_HUMAN (1-430): 0: 719: 90.23		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		883476 TBB4B_HUMAN (1-427): 0: 719: 91.10		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		883508 TBB3_HUMAN (1-442): 0: 719: 86.43		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		883632 TBB2B_HUMAN (1-430): 0: 719: 90.23		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		933974 TBB4B_HUMAN (1-427): 0: 719: 91.10		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		1046578 TBB2A_HUMAN (1-430): 0: 715: 90.00		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		381154 TBB4A_HUMAN (1-427): 0: 715: 90.16		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		381300 TBB4A_HUMAN (1-427): 0: 715: 90.16		Q9H4D1_HUMAN (8-175): 3.96e-31: 128: 18.54
+	Hs
		883510 TBB2A_HUMAN (1-430): 0: 715: 90.00		RIPK4_HUMAN (8-175): 2.18e-31: 128: 18.54
+	Hs
		1037272 TBB3_HUMAN (1-442): 0: 719: 86.43		ASB18_HUMAN (3-249): 5.75e-21: 96.6: 18.01
+	Hs
		1037398 TBB3_HUMAN (1-442): 0: 719: 86.43		ASB8_HUMAN (79-213): 2.57e-09: 60.1: 31.62