HitPredict

Interactor 1: TRXH3 (Q42403)
Thioredoxin H3 (AtTrxh3) (Thioredoxin 3) (AtTRX3)
Gene: TRX3

Interactor 2: PDI11 (Q9XI01)
Protein disulfide isomerase-like 1-1 (AtPDIL1-1) (EC 5.3.4.1) (Protein disulfide-isomerase 1) (PDI 1) (Protein disulfide-isomerase 5) (AtPDI5)
Gene: PDIL1-1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15352244
Identification Methods	enzymatic study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms	GO:0000325 - plant-type vacuole GO:0006457 - protein folding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 118 At			1 501
+	At
		1226367 TRXY2_ARATH (8-109): 1.24e-33: 116: 24.04		PDI11_ARATH (1-484): 6.57e-141: 416: 100.00
+	Hs
		423342 THIOM_HUMAN (9-113): 5.76e-34: 117: 31.78		PDIA1_HUMAN (22-479): 5.38e-122: 368: 35.47
+	Hs
		671722 PDIA3_HUMAN (3-117): 3.63e-28: 108: 22.31		PDIA3_HUMAN (6-500): 6.35e-124: 373: 31.97
+	Hs
		423107 PDIA1_HUMAN (4-110): 1.42e-26: 104: 20.35		PDIA1_HUMAN (22-479): 5.38e-122: 368: 35.47
+	Dm
		870451 THIO2_DROME (7-109): 1.88e-34: 116: 38.46		PDI_DROME (4-501): 3.4e-114: 347: 33.47
+	Ce
		1089129 PDI1_CAEEL (7-118): 9.74e-27: 104: 20.51		PDI2_CAEEL (5-480): 1.17e-117: 356: 32.44
+	Hs
		531830 PDIA4_HUMAN (2-112): 8.45e-26: 102: 23.73		PDIA5_HUMAN (1-501): 1.34e-75: 248: 16.88
+	Hs
		671862 PDIA3_HUMAN (3-117): 3.63e-28: 108: 22.31		DJC10_HUMAN (80-501): 1.37e-49: 183: 14.29
+	Hs
		423286 PDIA1_HUMAN (4-110): 1.42e-26: 104: 20.35		DJC10_HUMAN (80-501): 1.37e-49: 183: 14.29
+	Hs
		531897 PDIA4_HUMAN (2-112): 8.45e-26: 102: 23.73		DJC10_HUMAN (80-501): 1.37e-49: 183: 14.29
+	Hs
		671819 PDIA3_HUMAN (3-117): 3.63e-28: 108: 22.31		PDIA6_HUMAN (241-499): 1.02e-48: 175: 20.59
+	Hs
		531837 PDIA4_HUMAN (2-112): 8.45e-26: 102: 23.73		PDIA6_HUMAN (241-499): 1.02e-48: 175: 20.59
+	Hs
		531910 PDIA4_HUMAN (2-112): 8.45e-26: 102: 23.73		TXND5_HUMAN (12-142): 6.8e-31: 126: 33.59
+	Hs
		531739 PDIA3_HUMAN (3-117): 3.63e-28: 108: 22.31		PDIA4_HUMAN (339-501): 1.01e-25: 112: 27.71
+	Mm
		653446 PDIA3_MOUSE (3-116): 2.43e-27: 106: 20.83		ERP44_MOUSE (366-497): 8.84e-27: 113: 22.63
+	Mm
		1265101 TXND5_MOUSE (31-117): 7.29e-27: 104: 23.66		ERP44_MOUSE (366-497): 8.84e-27: 113: 22.63
+	Hs
		423123 PDIA1_HUMAN (4-110): 1.42e-26: 104: 20.35		PDIA4_HUMAN (339-501): 1.01e-25: 112: 27.71
+	Hs
		531966 PDIA4_HUMAN (2-112): 8.45e-26: 102: 23.73		ERP44_HUMAN (366-489): 4.96e-26: 111: 18.61