HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 30945288, 32140073, 31973889, 33961781, 37365982, 21145461, 18593899, 36688959, 31839598, 16964240, 23555860, 17041588
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Cullin, Cullin~Cullin_Nedd8
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0016567 - protein ubiquitination
and 7 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 759
Hs

1 913
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Service provided by Combinatics, Japan

Last updated: 11Aug2025