HitPredict

Interactor 1: CRY2 (Q49AN0)
Cryptochrome-2
Gene: CRY2

Interactor 2: FXL21 (Q9UKT6)
Putative F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box and leucine-rich repeat protein 3B) (F-box/LRR-repeat protein 3B)
Gene: FBXL21P

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	32937135, 24085301
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043153 - entrainment of circadian clock by photoperiod
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 434
+	Mm
		1206353 CRY2_MOUSE (18-593): 0: 810: 96.01		FXL21_MOUSE (1-434): 0: 771: 85.95
+	Mm
		1207952 CRY2_MOUSE (18-593): 0: 810: 96.01		FBXL3_MOUSE (17-434): 0: 727: 72.73
+	Hs
		1115767 CRY2_HUMAN (18-593): 0: 781: 100.00		FBXL3_HUMAN (30-434): 0: 733: 74.32
+	Hs
		1082162 CRY1_HUMAN (21-524): 0: 678: 80.75		FXL21_HUMAN (1-434): 0: 798: 100.00
+	Mm
		956903 CRY1_MOUSE (21-524): 0: 677: 80.16		FXL21_MOUSE (1-434): 0: 771: 85.95
+	Hs
		1082163 CRY1_HUMAN (21-524): 0: 678: 80.75		FBXL3_HUMAN (30-434): 0: 733: 74.32
+	Mm
		956905 CRY1_MOUSE (21-524): 0: 677: 80.16		FBXL3_MOUSE (17-434): 0: 727: 72.73