Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: Q7TN74 (Q7TN74)
Neurabin I (Neural tissue-specific F-actin binding protein) (Protein phosphatase 1, regulatory subunit 9A)
Gene: Ppp1r9a

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27507650, 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ_6, PDZ~SAM_1, SAM_1~SAM_2, PDZ~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0014069 - postsynaptic density
GO:0043197 - dendritic spine
GO:0044877 - protein-containing complex binding
GO:0050804 - modulation of chemical synaptic transmission
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1730
Mm

1 1095
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+ Ce

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Last updated: 15 Jul 2024