Protein: DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (EC 2.7.12.1) (Regulatory erythroid kinase) (REDK)

Gene: DYRK3
Organism: Homo sapiens
Interactions: 44
UniProt ID: O43781

Gene Ontology (top 5):
GO:0000242 - pericentriolar material
GO:0000287 - magnesium ion binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

227154

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

2

High-throughput

0.691

High

227157

RU2B
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.691

High

227164

NEK4
Serine/threonine-protein kinase Nek4

1

18

High-throughput

0.691

High

227186

SF3B6
Splicing factor 3B subunit 6

1

20

High-throughput

0.691

High

227175

SORL
Sortilin-related receptor

1

10

High-throughput

0.665

High

227148

DNJA2
DnaJ homolog subfamily A member 2

1

9

Small-scale

0.621

High

227160

DNJB1
DnaJ homolog subfamily B member 1

1

11

Small-scale

0.621

High

227180

ZN350
Zinc finger protein 350

1

2

Small-scale

0.621

High

156731

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.618

High

227150

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.618

High

227149

SNAPN
SNARE-associated protein Snapin

1

1

Small-scale

0.573

High

227182

GORS2
Golgi reassembly-stacking protein 2

2

6

High-throughput

0.553

High

131244

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

6

High-throughput

0.536

High

227153

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.536

High

227155

TPM3
Tropomyosin alpha-3 chain

1

20

High-throughput

0.536

High

227156

TPM2
Tropomyosin beta chain

1

17

High-throughput

0.536

High

227158

TPM1
Tropomyosin alpha-1 chain

1

18

High-throughput

0.536

High

227159

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.536

High

227161

SPB3
Serpin B3

1

4

High-throughput

0.536

High

227166

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

1

High-throughput

0.536

High

227167

TPM4
Tropomyosin alpha-4 chain

1

17

High-throughput

0.536

High

227168

DCTN2
Dynactin subunit 2

1

1

High-throughput

0.536

High

227177

TRM61
tRNA

1

3

High-throughput

0.536

High

227179

GSDMA
Gasdermin-A

1

1

High-throughput

0.536

High

227184

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

1

High-throughput

0.536

High

227181

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.513

High

227185

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.513

High

227174

FBX25
F-box only protein 25

1

2

Small-scale

0.501

High

227178

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

14

High-throughput

0.501

High

227165

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

1

High-throughput

0.489

High

227162

PGM1
Phosphoglucomutase-1

1

3

Small-scale

0.481

High

227173

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

20

Small-scale

0.481

High

227152

PRIO
Major prion protein

1

0

Small-scale

0.480

High

227147

GANP
Germinal-center associated nuclear protein

1

6

High-throughput

0.479

High

227169

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

Small-scale

0.479

High

227171

SMU1
WD40 repeat-containing protein SMU1

1

13

Small-scale

0.479

High

227176

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

12

Small-scale

0.479

High

104907

APRIO
Alternative prion protein

1

1

Small-scale

0.457

High

227151

FRIL
Ferritin light chain

1

3

High-throughput

0.445

High

227163

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

4

Small-scale

0.439

High

227183

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

1

7

Small-scale

0.439

High

227146

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.426

High

227170

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

227172

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025