Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: DLG1 (Q811D0)
Disks large homolog 1 (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97) (Synapse-associated protein 97) (SAP-97) (SAP97)
Gene: DLG1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27507650, 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1, PDZ~PDZ_6, PDZ~SAM_1, Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_1~SH3_2
Common GO terms GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0035255 - ionotropic glutamate receptor binding
GO:0043005 - neuron projection
GO:0098919 - structural constituent of postsynaptic density
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 905
+ Mm
+ Mm
+ Mm
+ Ce
+ Hs
+ Rn
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Rn
+ Rn
+ Hs
+ Mm
+ Hs

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Last updated: 15 Jul 2024