HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: MAP1S (Q8C052)
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) [Cleaved into: MAP1S heavy chain; MAP1S light chain]
Gene: MAP1S

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 973
+	Mm
		541464 SHAN3_MOUSE (1-1730): 0: 626: 100.00		MAP1B_MOUSE (513-973): 1.27e-44: 178: 20.35
+	Mm
		1116158 SHAN3_MOUSE (1-1730): 0: 626: 100.00		MAP1A_MOUSE (304-973): 2.03e-38: 158: 21.53
+	Mm
		292327 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ZAN_MOUSE (300-856): 1.43e-24: 113: 11.19
+	Mm
		93248 SHAN3_MOUSE (1-1730): 0: 626: 100.00		E9PWQ7_MOUSE (294-754): 6.98e-12: 72.3: 10.81
+	Mm
		88456 SHAN3_MOUSE (1-1730): 0: 626: 100.00		D3Z656_MOUSE (265-734): 9.52e-12: 71.5: 14.75
+	Mm
		936894 SHAN3_MOUSE (1-1730): 0: 626: 100.00		NACAM_MOUSE (286-860): 2.49e-11: 70.4: 9.72
+	Mm
		1116160 SHAN3_MOUSE (1-1730): 0: 626: 100.00		PCLO_MOUSE (502-946): 5.21e-09: 62.7: 10.99
+	Hs
		979984 SHAN3_HUMAN (1-1730): 0: 601: 95.21		IF4G1_HUMAN (417-865): 5.69e-10: 65.7: 12.27
+	Hs
		944702 SHAN3_HUMAN (1-1730): 0: 601: 95.21		MAP1A_HUMAN (338-885): 8.97e-10: 65.4: 10.95
+	Hs
		1056981 TNKS2_HUMAN (1-544): 1.02e-87: 315: 15.16		MDC1_HUMAN (412-857): 5.65e-09: 62.6: 13.19
+	Hs
		1115387 AKD1A_HUMAN (21-460): 3.05e-91: 309: 15.61		TITIN_HUMAN (457-867): 5.21e-10: 66: 10.45
+	Hs
		310053 TNKS1_HUMAN (12-400): 2.92e-79: 291: 16.63		MDC1_HUMAN (412-857): 5.65e-09: 62.6: 13.19
+	Dm
		65570 A8JNM5_DROME (19-638): 1.13e-74: 279: 14.72		FUTSC_DROME (809-973): 1.78e-12: 74.2: 27.49
+	Hs
		807690 ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64		MAP1B_HUMAN (510-973): 7.3e-43: 172: 20.00
+	Hs
		556716 ANK1_HUMAN (175-669): 2.17e-43: 176: 15.35		TITIN_HUMAN (457-867): 5.21e-10: 66: 10.45
+	Hs
		166985 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		TITIN_HUMAN (457-867): 5.21e-10: 66: 10.45
+	Dm
		113976 M9PB30_DROME (662-1371): 7.2e-27: 122: 15.27		M9PB30_DROME (304-687): 4.66e-11: 69.6: 9.12