HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: RBM8A (Q9Y5S9)
RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A)
Gene: RBM8A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 1 others more... GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 174
+	Hs
		1073582 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		SF3B4_HUMAN (67-149): 3.35e-25: 101: 28.92
+	Hs
		1116304 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PAP1L_HUMAN (64-158): 1.19e-24: 101: 24.21
+	Hs
		1031352 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		516541 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		1116542 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP3_HUMAN (64-158): 2.06e-21: 91.8: 23.16
+	Hs
		1054362 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		1031507 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		RBM8A_HUMAN (1-169): 1.46e-41: 138: 100.00
+	Hs
		1174880 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		RBM8A_HUMAN (1-169): 1.46e-41: 138: 100.00
+	At
		285476 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP2_ARATH (57-162): 3.6e-23: 97.2: 19.81
+	At
		285478 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP8_ARATH (70-158): 7.26e-22: 93.4: 22.47
+	At
		790116 LRP6C_ARATH (12-249): 1.53e-49: 179: 23.14		PABP2_ARATH (57-162): 3.6e-23: 97.2: 19.81
+	Hs
		403212 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		516689 PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		516495 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		516568 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		403225 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		403370 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		PPIE_HUMAN (74-160): 1.75e-17: 79.4: 31.03
+	Hs
		474021 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PAB4L_HUMAN (73-151): 1.5e-18: 83: 26.58
+	Hs
		1031328 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		1054393 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97